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2005, Número 2

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Rev Inst Nal Enf Resp Mex 2005; 18 (2)


Componentes glicosilados de la envoltura de Mycobacterium tuberculosis que intervienen en la patogénesis de la tuberculosis

Gorocica P, Jiménez-Martínez MC, Garfias Y, Sada I, Lascurain R

Idioma: Español
Referencias bibliográficas: 63
Paginas: 142-153
Archivo PDF: 212.77 Kb.


RESUMEN

Los componentes glicosilados de la envoltura de Mycobacterium tuberculosis tienen un papel importante en la inmunopatogénesis de la tuberculosis. Permiten la adhesión, penetración y persistencia de la micobacteria en el macrófago; de igual manera, participan en los mecanismos de activación de estas células y la producción de citocinas relevantes durante la respuesta inmune. En esta revisión, examinamos las características de las principales estructuras sacarídicas de la superficie de la micobacteria y su relación con la modulación de la respuesta inmune.


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