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Colegio de Medicina Interna de México.

2007, Número 4

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Med Int Mex 2007; 23 (4)


Medicamentos análogos de la insulina

Frenk BP, Escalante-Pulido M

Idioma: Español
Referencias bibliográficas: 78
Paginas: 310-320
Archivo PDF: 281.49 Kb.


RESUMEN

La mayor parte de los estudios ha demostrado que los pacientes con buen control glucémico disminuyen el padecimiento y la evolución de las retinopatías, nefropatías y neuropatías ocasionadas por la diabetes. La finalidad de los análogos de la insulina es controlar las concentraciones séricas de glucosa (hipoglucemia o hiperglucemia). Estos sustituyen ciertos aminoácidos en las cadenas a y b de la molécula de insulina que les confieren propiedades farmacodinámicas específicas, como: replicar el perfil más fisiológico de la insulina humana, mejorar el control glucémico y la calidad de vida de los pacientes. Esta revisión menciona las alternativas actuales relacionadas con los análogos de la insulina para el tratamiento de la diabetes mellitus.


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