2004, Número 3
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Alerg Asma Inmunol Pediatr 2004; 13 (3)
Bases inmunológicas actuales de la enfermedad de Kawasaki
Aviña FJA, López BR, Toro CJL
Idioma: Español
Referencias bibliográficas: 23
Paginas: 104-108
Archivo PDF: 129.43 Kb.
RESUMEN
La enfermedad de Kawasaki es una vasculitis sistémica de probable etiología infecciosa con una serie de respuestas inmunológicas en cascada, que producen un cuadro clínico caracterizado por fiebre elevada persistente de más de 5 días de evolución que no responde al manejo médico antipirético o antimicrobiano, y que se acompaña de por lo menos 4 de los siguientes criterios: conjuntivitis no exudativa, adenopatía cervical no supurada, cambios inflamatorios bucales con severo enrojecimiento y congestión de labios, lengua y orofaringe; erupción eritematosa morbiliforme con importante edema e inflamación en porción distal de las extremidades que posteriormente presenta descamación de la piel a nivel de los dedos. Este trabajo es una revisión de las bases inmunológicas actuales que resume los recientes resultados de las investigaciones reportadas en la literatura médica mundial; su objetivo es proporcionar un panorama de actualidad sobre los nuevos conocimientos que permiten una mejor comprensión en la respuesta inmunológica de la enfermedad de Kawasaki.
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