Miguel-Pérez P, Herrera-Hernández M, Padilla-Rodríguez A, Martínez-Consuegra N

Idioma: Español
Referencias bibliográficas: 32
Paginas: 517-522
Archivo PDF: 201.72 Kb.

RESUMEN

El cambio oncocítico es un agrandamiento del citoplasma ocasionado por la acumulación de mitocondrias, que se presenta en una amplia variedad de condiciones reactivas y neoplásicas. En la glándula tiroides, dicho cambio es un fenómeno de metaplasia que ocurre en distintas situaciones que provocan estrés celular y en ocasiones da lugar a verdaderas neoplasias benignas y malignas, entre las que destaca el adenoma oncocítico. A propósito de cuatro casos estudiados en el Departamento de Patología del Hospital ABC con características citomorfológicas inusuales que representaron un reto diagnóstico, hacemos una revisión del espectro morfológico de estos tumores. Las características presentadas incluyeron necrosis isquémica masiva posterior a toma de biopsia por aspiración, tamaño mayor al esperado en un adenoma, coexistencia con una neoplasia maligna independiente y características histológicas similares a las observadas en carcinoma papilar. Es de gran importancia para el patólogo conocer estas características, para evitar errores diagnósticos que puedan implicar un inadecuado manejo terapéutico.

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