Segura FAB, Miranda GO, León CI, Urgellés CSA, López FG, Rodríguez IG

Idioma: Español
Referencias bibliográficas: 20
Paginas:
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RESUMEN

Introducción: Las mujeres gestantes se identifican como un grupo vulnerable en cualquier brote de enfermedad infecciosa y presentan mayor probabilidad de desarrollar una enfermedad grave por COVID-19. Se describen múltiples factores de riesgo relacionados con la gravedad de esta enfermedad.
Objetivo: Determinar los predictores de gravedad en las pacientes obstétricas con COVID -19.
Métodos: Se realizó un estudio observacional analítico retrospectivo de caso y control en el Hospital Dr. Luis Díaz Soto, en el año 2021. El universo estuvo constituido por 632 pacientes, las que se dividieron en dos grupos: los casos constituidos por las pacientes obstétricas que presentaron resultados adversos graves y el control por pacientes obstétricas que no alcanzaron la gravedad. Ambos grupos se compararon basados en las variables constituidas por los predictores de gravedad por COVID-19.
Resultados: De 632 pacientes obstétricas con infección por SARS-CoV-2, 141 presentaron resultados maternos adversos y 491 pacientes desarrollaron formas no graves de la enfermedad. Fue mayor el riesgo de gravedad en gestantes del tercer trimestre (OR 2,4), con 35 años de edad o más (OR 2,1) y en portadoras de comorbilidades como: trastornos hipertensivos (OR 2,7), trastornos diabéticos (diabetes pregestacional y gestacional: OR 6,2), obesas (OR 6,9) y con marcadores de inflamación alterados.
Conclusiones: Las pacientes obstétricas con infección por SARS-CoV-2, mayores de 35 años de edad o más, en el tercer trimestre de la gestación, con presencia de comorbilidades e incremento de los biomarcadores inflamatorios, tienen mayor riesgo de presentar resultados adversos graves. Todos constituyen predictores de riesgo de gravedad para la COVID-19.

REFERENCIAS (EN ESTE ARTÍCULO)

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