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Antes Revista del Instituto Nacional de Enfermedades Respiratorias

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2007, Número S2

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Neumol Cir Torax 2007; 66 (S2)


Exacerbación infecciosa en la EPOC

Etiología de las exacerbaciones infecciosas
Etiología regional (México)
El papel de la resistencia bacteriana en el tratamiento de las exacerbaciones
Selección de antibióticos

Idioma: Español
Referencias bibliográficas: 45
Paginas: 71-76
Archivo PDF: 59.04 Kb.


FRAGMENTO

Dentro de la historia natural de la EPOC es esperado que los pacientes tengan “agudizaciones” o “exacerbaciones” de la enfermedad. Los procesos infecciosos bacterianos o virales son la causa más frecuente de este fenómeno, aunque no la única. Está demostrado que las exacerbaciones bacterianas se acompañan de mayor inflamación local y sistémica en contraste con las exacerbaciones no bacterianas produciendo un mayor deterioro de la capacidad funcional del paciente durante y después del evento, y poniendo en riesgo la vida. Aunque no es posible predecir de manera exacta cuáles pacientes son más propensos a tener exacerbaciones, se han identificado como factores de riesgo la presencia de síntomas cotidianos como tos y expectoración, el tabaquismo activo, el pobre apego al tratamiento y el antecedente de exacerbaciones previas. Estos factores son encontrados con mayor frecuencia en aquellos pacientes con más tiempo de padecer la EPOC y en aquellos con mayor severidad de la misma. Debido a que cada nuevo episodio de exacerbación acelera la progresión de la EPOC es muy importante el tratamiento adecuado de las mismas así como implementar medidas de prevención. En este apartado haremos recomendaciones respecto al manejo del componente infeccioso de las exacerbaciones. Le sugerimos revise las secciones previas de este consenso donde se tratan otros aspectos relevantes del manejo integral de esta complicación.


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