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Colegio de Medicina Interna de México.

2023, Número 3

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Med Int Mex 2023; 39 (3)


El efecto de la obesidad en pacientes quemados

Carrillo-Esper R, Islas-Ávila RE, González-Martínez KI

Idioma: Español
Referencias bibliográficas: 44
Paginas: 464-481
Archivo PDF: 265.74 Kb.


RESUMEN

Objetivo: Investigar el efecto de la obesidad en los pacientes quemados.
Metodología: Nuestra estrategia de revisión se desarrolló basada en los principios estándar de revisión sistemática mediante los ítems de referencias para publicar protocolos de revisiones sistemáticas y metanálisis (PRISMA) como guía para esta revisión.
Resultados: Se obtuvo una muestra final de 17 estudios disponibles para análisis. Se incluyeron 120,190 pacientes dentro de nuestra revisión sistemática.
Conclusiones: El paciente obeso quemado representa un reto en la reanimación hídrica, en la curación de la quemadura y en el manejo de la vía aérea, hemodinamia, ventilación, metabolismo, nutricional y perioperatorio, además del incremento en la morbilidad y mortalidad y de los días de estancia hospitalaria, en comparación con el paciente quemado sin obesidad o sobrepeso.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Ng M, Fleming T, Robinson M, Thomson B, et al. Global,regional, and national prevalence of overweight and obesityin children and adults during 1980–2013: a systematicanalysis for the Global Burden of Disease Study 2013. Lancet

  2. 2014; 384: 766-81. doi: 10.1016/S0140-6736(14)60460-8.2. Lobstein T, Rigby N, Rachel L. Obesity in Europe—3 InternationalObesity Task Force (IOTF). European Associationfor the Study of Obesity; 2005.

  3. Huang Z, Willett WC, Manson JE, Rosner B, et al. Bodyweight, weight change, and risk for hypertension in women.Ann Intern Med 1998; 128: 81-8. doi: 10.7326/0003-

  4. 4819-128-2-199801150-00001.4. World Health Organization: Obesity and Overweight. WHOFact Sheet No. 311, Geneva: WHO; 2015.

  5. Blüher M, Mantzoros CS. From leptin to other adipokines inhealth and disease: facts and expectations at the beginningof the 21st century. Metabolism 2015; 64 (1): 131-145. doi:10.1016/j.metabol.2014.10.016.

  6. Wang ZV, Scherer PE. Adiponectin, the past two decades.J Mol Cell Biol 2016; 8 (2): 93-100. doi: 10.1093/jmcb/mjw011.

  7. Naylor C, Petri WA Jr. Leptin regulation of immune responses.Trends Mol Med 2016 Feb; 22 (2): 88-98. doi:10.1016/j.molmed.2015.12.001.

  8. Schipper HS, Prakken B, Kalkhoven E, Boes M. Adiposetissue resident immune cells: key players in immunometabolism.Trends Endocrinol Metab 2012; 23 (8): 407-415.doi: 10.1016/j.tem.2012.05.011.

  9. Mraz M, Haluzik M. The role of adipose tissue immune cellsin obesity and low-grade inflammation. J Endocrinol 2014;222 (3): R113-127. doi: 10.1530/JOE-14-0283.

  10. Zheng C, Yang Q, Cao J, Xie N et al. Local proliferationinitiates macrophage accumulation in adipose tissue duringobesity. Cell Death Dis 2016; 7: e2167. doi: 10.1038/cddis.2016.54.

  11. Klöting N, Blüher M. Adipocyte dysfunction, inflammationand metabolic syndrome. Rev Endocr Metab Disord 2014;15 (4): 277-287. doi: 10.1007/s11154-014-9301-0.

  12. Flegal KM, Kit BK, Orpana H, Graubard BI. Associationof all cause mortality with overweight and obesity usingstandard body mass index categories: a systematic reviewand meta-analysis. JAMA 2013; 309: 71-82. doi: 10.1001/jama.2012.113905.

  13. Lurguin C. Quetelet’s scientific work. Science 1924; 60:351-2. doi: 10.1126/science.60.1555.351.

  14. Patel L, Cowden JD, Dowd D, Hampl S, Felich N. Obesity:influence on length of hospital stay for the pediatric burnpatient. J Burn Care Res 2010; 31: 251-6. doi: 10.1097/BCR.0b013e3181d0f549.

  15. Sheridan RL, Rue LW 3rd, McManus WF, Pruitt BA Jr. Burnsin morbidly obese patients. J Trauma 1992; 33 (6): 818-20.doi: 10.1097/00005373-199212000-00004.

  16. Ghanem AM, Sen S, Philp B, Dziewulski P, Shelley OP. BodyMass Index (BMI) and mortality in patients with severeburns: is there a “tilt point” at which obesity influencesoutcome? Burns 2011; 37 (2): 208-14. doi: 10.1016/j.burns.2010.08.010.

  17. Wilmore D, Pruitt BA Jr. Fat boys get burned. Lancet 1972;23: 631-2. doi: 10.1016/s0140-6736(72)93020-6.

  18. Barillo DJ, Burge TS, Harrington DT, Coffey EC, Shirani KZ,Goodwin CW. Body habitus as a predictor of burn risk inchildren: do fat boys still get burned? Burns 1998; 24: 725-7. doi: 10.1016/s0305-4179(98)00088-6.

  19. Goutos I, Sadideen H, Pandya A, Ghosh S. Obesity andburns. J Burn Care Res 2012; 33: 471-82. doi: 10.1097/BCR.0b013e318247959b.

  20. Lumenta D, Hautier A, Desouches C, Gouvernet J, GiorgiR, Manelli J, et al. Mortality and morbidity among elderlypeople with burns—evaluation of data on admission. Burns2008; 34: 965-74. doi: 10.1016/j.burns.2007.12.004.

  21. McCampbell B, Wasif N, Rabbitts A, Staiano-Coico L,Yurt R, Schwartz S. Diabetes and burns: retrospectivecohort study. J Burn Care Rehabil 2002; 23:157-66. doi:10.1097/00004630-200205000-00004.

  22. Kalantar-Zadeh K, Block G, Horwich T, Fonarow GC. Reverseepidemiology of conventional cardiovascular risk factorsin patients with chronic heart failure. J Am Coll Cardiol2004; 43 (8): 1439-1444. doi: 10.1016/j.jacc.2003.11.039.

  23. Kalantar-Zadeh K, Block G, Humphreys MH, Kopple JD.Reverse epidemiology of cardiovascular risk factors inmaintenance dialysis patients. Kidney Int 2003; 63 (3):793-808. doi: 10.1046/j.1523-1755.2003.00803.x.

  24. Amptoulach S, Gross G, Kalaitzakis E. Differential impactof obesity and diabetes mellitus on survival after liver resectionfor colorectal cancer metastases. J Surg Res 2015;199 (2): 378-385. doi: 10.1016/j.jss.2015.05.059.

  25. Li S, Wang Z, Huang J, Fan J, et al. Systematic review ofprognostic roles of body mass index for patients undergoinglung cancer surgery: does the “obesity paradox”really exist? Eur J Cardiothorac Surg 2017; 51 (5): 817-828.https://doi.org/10.1093/ejcts/ezw386.

  26. Rosenthal J, Clark A, Campbell S, McMahon M, ArnoldoB, Wolf SE, Phelan H. Effects of obesity on burn resuscitation.Burns 2018; 44 (8): 1947-1953. doi: 10.1016/j.burns.2018.06.002., 1-7.

  27. Liu NT, Fenrich CA, Serio-Melvin ML, Peterson WC, CancioLC, Salinas J. The impact of patient weight on burn resuscitation.J Trauma Acute Care Surg 2017; 83: S112-S119.doi: 10.1097/TA.0000000000001486.

  28. Sayampanathan AA. Systematic review and meta-analysisof complications and outcomes of obese patients withburns. Burns 2016; 42 (8): 1634-1643. doi: 10.1016/j.burns.2016.05.008.

  29. Ray JJ, Satahoo SS, Meizoso JP, Allen CJ, Teisch LF, ProctorKG, Pizano LR, Namias N, Schulman CI. Does obesity affectoutcomes of adult burn patients? J Surg Res 2015; 198:450-455. doi: 10.1016/j.jss.2015.03.049.

  30. Ross E, Burris A, Murphy JT. Obesity and outcomes followingburns in the pediatric population. J Pediatr Surg2014; 49: 469-473. doi: 10.1016/j.jpedsurg.2013.07.012.

  31. Liodaki E, Senyaman O, Stollwerck PL, Mollmeier D, MaussKL, Mailander P, Stang F. Obese patients in a burn careunit: A major challenge. Burns 2014; 40: 1738-1742. doi:10.1016/j.burns.2014.04.016.

  32. Jeschke MG, Finnerty CC, Emdad F, Rivero HG, Kraft R,Williams FN, Gamelli RL, Gibran NS, Klein MB, ArnoldoBD, Tompkins RG, Herndon DN, and The Inflammationand the Host Response to Injury Collaborative ResearchProgram. Mild obesity is protective after severe burninjury. Ann Surg 2013; 258 (6): 1119-1129. doi: 10.1097/SLA.0b013e3182984d19.

  33. Rae L, Pham TN, Carrougher G, Honari S, Gibran NS, ArnoldoBD, Gamelli RL, Tompkins RG, Herndon DN. Differencesin resuscitation in morbidly obese burn patients maycontribute to high mortality. J Burn Care Res 2013; 34 (5):507-514. doi: 10.1097/BCR.0b013e3182a2a771.

  34. Kraft R, Herndon DN, Williams FN, Al-Mousawi AM, FinnertyCC, Jeschke MG. The effect of obesity on adverse outcomesand metabolism in pediatric burn patients. Int J Obes2012; 36: 485-490. https://doi.org/10.1038/ijo.2011.224.

  35. Farrell RT, Gamelli RL, Aleem RF, Sinacore JM. The relationshipof body mass index and functional outcomes in patientswith acute burns. J Burn Care Res 2008; 29: 102-108. doi:10.1097/BCR.0b013e31815f5984.

  36. Carpenter AM, Hollett LP, Jeng JC, Wu J, Turner DG, JordanMH. How long a shadow does epidemic obesity cast inthe burn unit? A dietitian’s analysis of the strengths andweaknesses of the available data in the national burn repository.J Burn Care Res 2008; 29: 97-101. doi: 10.1097/BCR.0b013e31815f59b1.

  37. Livingston E.H, Lee S. Percentage of burned body surfacearea determination in obese and nonobese patients. J SurgRes 2000: 91 (2). doi: 10.1006/jsre.2000.5909.

  38. Tapking C, Houschyar KS, Rontoyanni V, Hundeshagen G,Kowalewski KF, et al. The influence of obesity on treatmentand outcome of severely burned patients. J Burn Care Res2019; 40 (6): 996-1008. doi: 10.1093/jbcr/irz115..

  39. Rios-Diaz AJ, Lin E, Williams K, Jiang W, et al. The obesityparadox in patients with severe soft tissue infections.Am J Surg 2017; 214 (3): 385-389. doi: 10.1016/j.amjsurg.2016.05.006.

  40. Davos CH, Doehner W, Rauchhaus M, Cicoira M, et al. Bodymass and survival in patients with chronic heart failurewithout cachexia: The importance of obesity. J Card Fail2003; 9: 29-35. doi: 10.1054/jcaf.2003.4.

  41. Fantuzzi G. Adipose tissue, adipokines, and inflammation.J Allergy Clin Immunol 2005; 115: 911-9; quiz 920. doi:10.1016/j.jaci.2005.02.023.

  42. Lester EL, Dvorak JE, Maluso PJ, Bendjemil S, Messer T,Poulakidas S, Bokhari F. Obesity paradox in the burn patient.J Burn Care Res 2020; 41 (1): 30-32. doi: 10.1093/jbcr/irz173.

  43. Keshavarzi A, Kardeh S, Dehghankhalili M, Varahram MH,Omidi M, Zardosht M, Mehrabani D. Mortality and bodymass index in burn patients: Experience from a tertiaryreferral burn center in Southern Iran. BMI in Iranian burnpatients. World J Plast Surg 2019; 8 (3): 382-397. doi:10.29252/wjps.8.3.382.

  44. Pauzenberger R, Radtke C, Ederer IA, Hacker S, WaldmannA, Sternat N, Franke I, Thury A, Harpain L, Stievano S. Doesobesity impact the outcome of severely burned patients?Int Wound J 2020; 17: 380-386. doi: 10.1111/iwj.13282




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