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2003, Número 4

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Rev ADM 2003; 60 (4)


Posible papel de Mycoplasma salivarium y Mycoplasma fermentans en la periodontitis

Rivera TJA, Román MC

Idioma: Español
Referencias bibliográficas: 23
Paginas: 142-144
Archivo PDF: 53.28 Kb.


RESUMEN

Mycoplasma salivarium y Mycoplasma fermentans inducen IL-lß y factor de necrosis tumoral-alfa en monocitos y macrófagos, los cuales son capaces de inducir la expresión de ICAM-1 en fibroblastos gingivales y la producción de IL-6 e IL-8 en fibroblastos gingivales. Se especula que ambos micoplasmas tienen un papel importante en la etiología de la enfermedad periodontal, ya que facilitan la infiltración, acumulación o retención de células inflamatorias en el tejido conectivo gingival.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Socransky SS, Halfajee AD. Evidence of bacterial etiology: a historical perspective. Periodontol 1994; 5: 7-25.

  2. Wilson MJ, Weightman AJ, Walde WG. Application of molecular ecology in the characterization of uncultured microorganisms associated with human disease. Rev Med Microbiol 1997; 8: 91-101.

  3. Pace NR, Stahl DA, Lane DJ, Olsen GJ. The analysis of natural microbial populations by ribosomal RNA sequences. Adv Microb Ecol 1986; 9: 1-55.

  4. Slots J, Genco RJ. Microbial pathogenicity: black-pigmented Bacteroides species, Capnocytophaga species and Actinobacillus actinomycetemcomitans in human periodontal disease: virulence factors in colonization, survival, and tissue destruction. J Dent Res 1984; 63: 412-421.

  5. Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA. Induction by IL-1 and interferon: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J Immunol 1986; 137: 245-254.

  6. Razin S, Yogev D, Naot Y. Molecular biology and pathogenicity of mycoplasmas. Microbiol Mol Biol Rev 1998; 62: 1138-114.

  7. Steffen MJ, Holt SC, Ebersole JL. Porphyromonas gingivalis induction of mediator and cytokine secretion by human gingival fibroblasts. Oral Microbiol Immunol 2000; 15: 172-180.

  8. Baker PJ, Dixon M, Evans RT, Dufour L, Johnson E, Roopeinan DC. CD4+ T cells and the proinflammatory cytokines gamma interferon and inteleukin-6 contribute to alveolar bone loss in mice. Infect Immun 1999; 67: 2804-2809.

  9. Krause DC, Taylor-Robinson D. Mycoplasmas which infect humans. In: Maniloff J, McElhaney RN, Finch LR, Baseman JB (ed). Mycoplasmas: molecular biology and pathogenesis. Washington, D.C. American Society for Microbiology. 1992: 417-444.

  10. Engel LD, Kenny GE. Mycoplasma salivarium in human gingival sulci. J Periodontal Res 1970; 5: 163-171.

  11. Watanabe T, Matsuura M, Seto K. Enumeration, isolation and species identification of mycoplasmas in saliva sampled from the normal and pathological human oral cavity and antibody response to an oral mycoplasma (Mycoplasma salivarium). J Clin Microbiol 1992; 23: 1034-1038.

  12. McGarrity GJ, Kotani H, Butler GH. Mycoplasmas and tissue culture cells. In: Maniloff J, McElhaney RN, Finch LR, Baseman JB (ed). Mycoplasmas: molecular biology and pathogenesis. Washington, D.C. American Society for Microbiology. 1992: 445-454.

  13. Shibata KI, Hasebe A, Sasaki T, Watanabe T. Mycoplasma salivarium induces interleukin-6 and interleukin-8 in human gingival fibroblasts. FEMS Immunol Med Microbiol 1998; 19: 275-283.

  14. Chingbingyong MI, Huges CV. Detection of Mycoplasma fermentans in human saliva with polymerase chain reaction-based assay. Arch Oral Biol 1997; 41: 311-314.

  15. Dong L. Shibata KI, Sawa Y, Hasebe A, Yamaoka Y, Yoshida S, Watanabe T. Transcriptional activation of mRNA of intercellular adhesion molecule 1 and induction of its cells surface expression in normal human gingival fibroblasts by Mycoplasma salivarium and Mycoplasma fermentans. Infection Immun 1999; 67: 3061-3065.

  16. Muhlrardt PF, Kieb M, Meyer H, Submuth R, Jung G. Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration. J Exp Med 1997; 185: 1951-1958.

  17. Shibata KI, Kaga M, Kudo M, Dong L, Hasebe A, Domon H, Sato Y, Oguchi H, Watanabe T. Detection of Mycoplasma fermentans in saliva sampled from infants, preschool and school children, adolescents and adults by a polymerase chain reaction based assay. Microbiol Immunol 1999; 43: 521-525.

  18. Watanabe T, Shibata KI, Yoshikawa T, Dong L, Hasebe A, Domon H, Kobayashi T, Totsuka Y. Detection of Mycoplasma fermentans in synovial fluids of temporomandibular joints of patients with disorders in the joints. FEMS Immunol Med Microbiol 1998; 22: 241-246.

  19. Henry CH, Hughes V, Gerard HC, Hudson AP, Wolford M. Reactive arthritis: preliminary microbiologic analysis of the human temporomandibular joint. J Oral Maxillofac Surg 2000; 58: 1137-1142.

  20. Gemmell EL, Walsh J, Savage NW, Seymour GJ. Adhesion molecule expression in chronic inflammatory periodontal disease tissue. J Periodontal Res 1994; 29: 46-53.

  21. Hayashi J, Saito I, Ishikawa I, Miyasaka N. Effects of cytokines and periodontopathic bacteria on the leukocyte function-associated antigen 1/intercellular adhesion molecule 1 pathway in gingival fibroblasts in adult periodontitis. Infect Immun 1994; 62: 5205-5212.

  22. Takeuchi Y, Sakurai K, Ike I, Yoshie H, Kawasaki K, Hara K. ICAM-1 expressing pocket epithelium, LFA-1 expressing T cells in gingival tissue and gingival crevicular fluid as features characterizing inflammatory cell invasion and exudation in adult periodontitis. J Periodontal Res 1995; 30: 426-435.

  23. Paster BJ, Boches SK, Galvin JL, Ericson RE, Lau CN, Levanos VA, Sahasrabudhe A, Dewhirst FE. Bacterial diversity in human subgingival plaque. J Bacteriol 2001; 183: 3770-3783.




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