2022, Número 6
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Med Int Mex 2022; 38 (6)
Oxigenoterapia no invasiva en pacientes con COVID-19: wu ji bi fan: mucho de algo no es bueno
Sánchez-Díaz JS, Peniche-Moguel KG, Betancourt-Vera JE, Carballo-Molina L, Vargas-García IJ, García-García VM, Martínez-Aguilar FR, Calyeca-Sánchez MV
Idioma: Español
Referencias bibliográficas: 46
Paginas: 1244-1253
Archivo PDF: 244.12 Kb.
RESUMEN
En la práctica clínica, el oxígeno puede salvar vidas, aunque
wu ji bi fan: mucho de
algo no es bueno y también puede causar toxicidad. El 14% de los pacientes con
enfermedad por coronavirus 2019 (COVID-19) tendrá necesidad de oxigenoterapia
no invasiva y aproximadamente el 5% requerirá ventilación mecánica invasiva. La
oxigenoterapia no invasiva es el tratamiento de primera línea para pacientes con insuficiencia
respiratoria aguda hipoxémica secundaria a COVID-19. Los dispositivos a
través de los cuales se administra esta terapéutica se clasifican en bajo flujo y alto flujo.
En presencia de insuficiencia respiratoria aguda hipoxémica, el flujo necesario puede
ser de 30 a 120 L/min, cifra que no puede alcanzarse con sistemas convencionales
(bajo flujo), entonces, los dispositivos de alto flujo pueden ser efectivos en pacientes
bien seleccionados, teniendo como objetivo mejorar la oxigenación, evitar la intubación
orotraqueal del paciente, pero sin retrasarla. La oxigenoterapia no invasiva no
incrementa el riesgo de infección por aerosoles.
REFERENCIAS (EN ESTE ARTÍCULO)
Heffner JE. The story of oxygen. Respir Care 2013; 58 (1):18-31. doi: 10.4187/respcare.01831.
Sena LA, Chandel NS. Physiological roles of mitochondrialreactive oxygen species. Mol Cell 2012; 48 (2): 158-67. doi:10.1016/j.molcel.2012.09.025.
Bitterman H. Bench-to-bedside review: oxygen as a drug.Crit Care 2009; 13 (1): 205. doi: 10.1186/cc7151.
Nakane M. Biological effects of the oxygen molecule incritically ill patients. J Intensive Care 2020; 8 (1): 95. https://doi.org/10.1186/s40560-020-00505-9.
Zubieta-Calleja G, Zubieta-De Urioste N. Pneumolysis and“silent hypoxemia” in COVID-19. Indian J Clin Biochem2020; 36 (1): 1-5. doi: 10.1007/s12291-020-00935-0.
Organización Mundial de la Salud (OMS). Clinical managementof severe acute respiratory infection (SARI) when COVID-19 disease is suspected. Interim guidance 2020; 5: 19.
O’Driscoll BR, Howard LS, Earis J, Mak V. British ThoracicSociety Guideline for oxygen use in adults in healthcareand emergency settings. BMJ Open Respir Res 2017; 4 (1):e000170. doi: 10.1136/bmjresp-2016-000170.
Arora S, Tantia P. Physiology of oxygen transport and itsdeterminants in intensive care unit. Indian J Crit CareMed 2019; 23 (Suppl 3): S172-S177. doi: 10.5005/jpjournals-10071-23246.
Sousa JS, D’Imprima E, Vonck J. Mitochondrial respiratorychain complexes. Subcell Biochem 2018; 87: 167-227. doi:
10.1007/978-981-10-7757-9_7.10. Sarkar M, Niranjan N, Banyal PK. Mechanisms of hypoxemia.Lung India 2017; 34 (1): 47-60. doi: 10.4103/0970-2113.197116.
Koch CJ, Evans SM. Optimizing hypoxia detection andtreatment strategies. Semin Nucl Med 2015; 45 (2): 163-176. doi: 10.1053/j.semnuclmed.2014.10.004.
Young PJ, Bellomo R. The risk of hyperoxemia in ICU patients.Much ado about O2. Am J Respir Crit Care Med 2019;200 (11): 1333-1335. doi: 10.1164/rccm.201909-1751ED.
Pizzino G, Irrera N, Cucinotta M, Pallio G, et al. Oxidativestress: Harms and benefits for human health. Oxid Med CellLongev 2017; 2017: 8416763. doi: 10.1155/2017/8416763.
Nouri-Vaskeh M, Sharifi A, Khalili N, Zand R, et al. Dyspneicand non-dyspneic (silent) hypoxemia in COVID-19: Possibleneurological mechanism. Clin Neurol Neurosurg 2020; 198:106217. doi: 10.1016/j.clineuro.2020.106217.
Leeies M, Flynn E, Turgeon AF, Paunovic B, et al. High-flowoxygen via nasal cannulae in patients with acute hypoxemicrespiratory failure: a systematic review and meta-analysis.Syst Rev 2017; 6 (1): 202. doi: 10.1186/s13643-017-0593-5.
Jaber S, Citerio G, Slutsky AS. Acute respiratory failure andmechanical ventilation in the context of the COVID-19pandemic: why a special issue in ICM? Intensive CareMed 2020; 46 (12): 2131-2132. doi: 10.1007/s00134-020-06298-7.
Nishimura M. High-flow nasal cannula oxygen therapy inadults: physiological benefits, indication, clinical benefits,and adverse effects. Respir Care 2016; 61: 529-541. doi:10.4187/respcare.04577.
Rochwerg B, Einav S, Chaudhuri D, et al. The role for highflow nasal cannula as a respiratory support strategy inadults: a clinical practice guideline. Intensive Care Med2020; 46 (12): 2226-2237. doi: 10.1007/s00134-020-06312-y.
Masclans JR, Pérez-Terán P, Roca O. The role of high flowoxygen therapy in acute respiratory failure. Med Intensiva
2015; 39 (8): 505-15.20. González-Castro A, Fajardo Campoverde A, Medina A,Modesto V, et al. Ventilación mecánica no invasiva yoxigenoterapia de alto flujo en la pandemia COVID-19:El valor de un empate. Med Intensiva (Engl Ed). 2021; 45(5): 320-321. Spanish. doi: 10.1016/j.medin.2020.04.017.
Frat J-P, Thille AW, Mercat A, Girault C, et al. High-flowoxygen through nasal cannula in acute hypoxemic respiratoryfailure. N Engl J Med 2015; 372: 2185-96. http://dx.doi.org/10.1056/NEJMoa1503326.
WHO. Clinical management of severe acute respiratoryinfection when novel coronavirus (2019-nCoV) infectionis suspected. Disponible en: https://www.who.int/docs/defaultsource/ coronaviruse/clinical-management-ofnovel-cov.pdf [Consultado el 22 de abril de 2020].
Beng-Leong L, Wei Ming N, Wei Feng L. High flow nasal cannulaoxygen versus noninvasive ventilation in adult acuterespiratory failure: a systematic review of randomizedcontrolledtrials. Eur J Emerg Med 2019; 26 (1): 9-18. doi:10.1097/MEJ.0000000000000557.
Roca O, Messika J, Caralt B, Garcia-de Acilu M, et al. Predictingsuccess of high-flow nasal cannula in pneumoniapatients with hypoxemic respiratory failure: The utility ofthe ROX index. J Crit Care 2016; 35: 200-5. doi: 10.1016/j.jcrc.2016.05.022.
Guia MF, Boléo-Tomé JP, Imitazione P, Polistina GE, et al.Usefulness of the HACOR score in predicting success ofCPAP in COVID-19-related hypoxemia. Respir Med 2021;187: 106550. doi:10.1016/j.rmed.2021.106550.
Grieco DL, Maggiore SM, Roca O, Spinelli E, et al. Noninvasiveventilatory support and high-flow nasal oxygen asfirst-line treatment of acute hypoxemic respiratory failureand ARDS. Intensive Care Med 2021; 47: 851-866. doi:10.1007/s00134-021-06459-2.
Tobin MJ. Basing respiratory management of COVID-19 onphysiological principles. Am J Respir Crit Care Med 2020;201 (11): 1319-1320. doi: 10.1164/rccm.202004-1076ED.
Demiselle J, Calzia E, Hartmann C, Messerer D, et al. Targetarterial PO2 according to the underlying pathology: a minireviewof the available data in mechanically ventilatedpatients. Ann Intensive Care 2021; 11 (1): 88. doi:10.1186/s13613-021-00872-y.
Shenoy N, Luchtel R, Gulani P. Considerations for targetoxygen saturation in COVID-19 patients: are weunder-shooting? BMC Med 2020; 18: 260. https://doi.org/10.1186/s12916-020-01735-2.
Barrot L, Asfar P, Mauny F, Winiszewski H, et al. Liberal orconservative oxygen therapy for acute respiratory distresssyndrome. N Engl J Med 2020; 382 (11): 999-1008. doi:10.1056/NEJMoa1916431.
Chu DK, Kim LH, Young PJ, Zamiri N, et al. Mortality andmorbidity in acutely ill adults treated with liberal versusconservative oxygen therapy (IOTA): a systematic reviewand meta-analysis. Lancet 2018; 391 (10131): 1693-1705.doi: 10.1016/S0140-6736(18)30479-3.
Thomson L, Paton J. Oxygen toxicity. Paediatr Respir Rev.2014 Jun;15(2):120-3. doi: 10.1016/j.prrv.2014.03.003.
Tobin MJ. Generalizability and singularity. The crossroadsbetween science and clinical practice. Am J Respir Crit CareMed 2014; 189 (7): 761-2. doi: 10.1164/rccm.201403-0408ED.
Blez D, Soulier A, Bonnet F, Gayat E, Garnier M. Monitoringof high-flow nasal cannula for SARS-CoV-2 severepneumonia: less is more, better look at respiratory rate.Intensive Care Med 2020; 46 (11): 2094-2095. doi:10.1007/s00134-020-06199-9.
Tobin MJ, Jubran A, Laghi F. PaO2/FIO2 ratio: the mismeasureof oxygenation in COVID-19. Eur Respir J 2021; 57 (3):2100274. doi:10.1183/13993003.00274-2021.
Tobin MJ. Basing respiratory management of COVID-19 onphysiological principles. Am J Respir Crit Care Med 2020;201 (11): 1319-1320. doi: 10.1164/rccm.202004-1076ED.
Mellado-Artigas R, Ferreyro BL, Angriman F, Hernandez-Sanz M, et al. High-flow nasal oxygen in patients with COVID-19-associated acute respiratory failure. Crit Care 2021;25: 58. https://doi.org/10.1186/s13054-021-03469-w.
Roca O, Caralt B, Messika J, Samper M, et al. An index combiningrespiratory rate and oxygenation to predict outcomeof nasal high-flow therapy. Am J Respir Crit Care Med 2019;199 (11): 1368-1376. doi: 10.1164/rccm.201803-0589OC.
Ricard JD, Roca O, Lemiale V, Corley A, et al. Use of nasalhigh flow oxygen during acute respiratory failure. IntensiveCare Med 2020; 46 (12): 2238-2247. doi:10.1007/s00134-020-06228-7.
Guan L, Zhou L, Le Grange JM, Zheng Z, et al. Non-invasiveventilation in the treatment of early hypoxemic respiratoryfailure caused by COVID-19: considering nasal CPAP asthe first choice. Crit Care 2020; 24: 333. doi: 10.1186/s13054-020-03054-7.
Fu Y, Guan L, Wu W, Yuan J, et al. Noninvasive ventilationin patients with COVID-19-related acute hypoxemicrespiratory failure: A retrospective cohort study.Front Med (Lausanne) 2021; 8: 638201. doi: 10.3389/fmed.2021.638201.
Bellani G, Grasselli G, Cecconi M, Antolini L, et al. Noninvasiveventilatory support of patients with COVID-19 outsidethe intensive care units (WARd-COVID). Ann Am Thorac Soc2021; 18 (6): 1020-1026. doi: 10.1513/AnnalsATS.202008-1080OC.
Grieco DL, Menga LS, Cesarano M, Rosa T, et al. Effect of helmetnoninvasive ventilation vs high-flow nasal oxygen ondays free of respiratory support in patients with COVID-19and moderate to severe hypoxemic respiratory failure: TheHENIVOT randomized clinical trial. JAMA 2021; 325 (17):1731-1743. doi:10.1001/jama.2021.4682.
Duan J, Han X, Bai L. Assessment of heart rate, acidosis,consciousness, oxygenation, and respiratory rate to predictnoninvasive ventilation failure in hypoxemic patients.Intensive Care Med 2017; 43 (2): 192-199. doi: 10.1007/s00134-016-4601-3.
Coppo A, Bellani G, Winterton D. Feasibility and physiologiceffects of prone positioning in non-intubated patients withacute respiratory failure due to COVID-19 (PRON-COVID):a prospective cohort study. Lancet Respir Med 2020. doi:10.1016/S2213-2600(20)30268-X.
Li J, Fink JB, Ehrmann S. High-flow nasal cannula for COVID-19 patients: low risk of bio-aerosol dispersion. Eur RespirJ 2020; 55 (5): 2000892. doi:10.1183/13993003.00892-2020.