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2022, Número 1

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Rev Educ Bioquimica 2022; 41 (1)


Las lectinas como herramientas en biomedicina

Gallegos VIB, Fernández RB, Vázquez AV, Sánchez CMD, Lopez CMS, García CLM, Santiago OBL, Hernández CPA

Idioma: Español
Referencias bibliográficas: 65
Paginas: 18-27
Archivo PDF: 816.94 Kb.


RESUMEN

Las lectinas son proteínas o glicoproteínas que reconocen de manera específica carbohidratos de la superficie celular o en suspensión, aglutinan células y precipitan glicoconjugados. Las lectinas no poseen actividad enzimática y presentan actividades biológicas, diversas como son: la aglutinación de eritrocitos de diferentes especies, la estimulación mitogénica de linfocitos e inhibición de la fagocitosis. Las lectinas aisladas de diversas fuentes vegetales o animales, han demostrado ser herramientas útiles en la investigación biomédica, en donde se les utiliza para la tipificación de grupos sanguíneos, aislamientos de poblaciones, caracterización de nuevos antígenos.


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