2022, Número 2
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salud publica mex 2022; 64 (2)
Asociación del virus del papiloma humano de alto riesgo con la neoplasia escamosa de la superficie ocular: estudio de casos y controles en México
De La Parra-Colin P, Pichardo-Bahena R, Méndez-Martínez R, García-Carrancá A, Santamaría-Olmedo M, Barrientos-Gutiérrez T, Lazcano-Ponce E, Hidalgo-Bravo A
Idioma: Ingles.
Referencias bibliográficas: 42
Paginas: 209-217
Archivo PDF: 279.11 Kb.
RESUMEN
Objetivo. Investigar la asociación del virus del papiloma
humano de alto riesgo (VPH-AR), así como de otros factores,
con neoplasia escamosa de la superficie ocular (NESO).
Material y métodos. Se obtuvieron 22 especímenes de
tejido fresco de NESO y 22 de pterigión como controles;
se utilizó una técnica molecular altamente sensible para
identificar la infección por VPH en todos los especímenes,
así como la genotipificación del VPH. También se obtuvo
información demográfica sobre exposición a la luz solar y
tabaquismo.
Resultados. La frecuencia de infección por
VPH-AR fue de 40.9% en el grupo de NESO y de 4.5% en el
grupo control (
p=0.009). Después de ajustar por covariables,
NESO se asoció con el VPH-AR (OR=16.3, IC95%=1.2,218.1,
p=0.03) y el eritema solar (OR=10.8, IC95%=1.8,86.0,
p=0.02).
Conclusiones. La neoplasia escamosa de superficie ocular
en una neoplasia multifactorial. Los presentes resultados
sugieren que el VPH-AR podría tener un papel etiológico en
el desarrollo de NESO.
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