2022, Número 1
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Dermatología Cosmética, Médica y Quirúrgica 2022; 20 (1)
Síndrome de las uñas verdes: una revisión
Sierra-Maeda KY, Segundo-López LD, Vega DC, Juárez DÉR, Arenas R
Idioma: Español
Referencias bibliográficas: 52
Paginas: 78-85
Archivo PDF: 584.48 Kb.
RESUMEN
El síndrome de uñas verdes, o síndrome Goldman-Fox, originalmente
fue descrito en 1944 por Goldman y Fox, es un padecimiento
ungueal poco frecuente, los conocimientos sobre
su fisiopatología, etiología y tratamiento se basan en pocos
reportes de casos. Se caracteriza por un cambio en la coloración
de la lámina ungueal, onicólisis y paroniquia, entre otras
alteraciones que pueden variar de acuerdo con la etiología. Las
causas son principalmente infecciones bacterianas en las que
destaca
Pseudomonas aeruginosa, sin embargo, se han reportado
levaduras como
Candida spp., hongos no dermatofitos y bacilos
gram negativos diferentes a
Pseudomonas spp., así como productos
químicos.
El diagnóstico se basa en la exploración clínica, medios de
cultivo, y recientemente se destaca la importancia de la dermatoscopia
en su identificación. El tratamiento varía de acuerdo
con la etiología y se incluyen tratamientos con antibióticos tópicos,
o sistémicos, antimicóticos y medidas generales.
REFERENCIAS (EN ESTE ARTÍCULO)
Fawcett RS, Linford S y Stulberg DL, Nail abnormalities: clues to systemic disease, Am Fam Physician 2004; 69:1417-24.
Gish D y Romero BJ, Green fingernail, J Fam Pract 2017; 66(5):e7-e9.
Schwartz RA y Kapila R, The Goldman-Fox syndrome: treating and preventing green pseudomonas nails in the area of covid-19, Dermatol Therap 2020; 10:e14624.
Geizhals S y Lipner SR, Retrospective case series on risk factors, diagnosis and treatment of Pseudomonas aeruginosa nail infections, Am J Clin Dermatol 2020; 21(2):297-302.
Nenoff P, Paasch U y Handrick W, Infections of finger and toenails due to fungi and bacteria, Hautarzt 2014; 65: 337-48.
Chiriac AE, Chiriac A y Wollina U, Chloronychia in healthcare workers in covid-19 times, Skin Appendage Disord 2021; 7(1):80-1.
Chiriac A, Brzezinski P, Foia L y Marincu I, Chloronychia: green nail syndrome caused by Pseudomonas aeruginosa in elderly persons, Clin Interv Aging 2015; 10:265-7.
Monteagudo B, Figueroa O, Suárez-Magdalena O y Méndez-Lage S, Green nail caused by onychomycosis coinfected with Pseudomonas aeruginosa, Actas Dermosifiliogr 2019; 110(9):783-5.
Hengge UR y Bardeli V, Images in clinical medicine. Green nails, N Engl J Med 2009; 360(11):1125.
Pier GB y Ramphal R, Pseudomonas aeruginosa. En Mandell GL, Bennett JE y Dolin R (eds.), Principles and practice of infectious diseases, 6ª ed., Filadelfia, Churchill Livingstone, 2004.
Müller S, Ebnöther M e Itin P, Green nail syndrome (Pseudomonas aeruginosa nail infection): two cases successfully treated with topical nadifloxacin, an acne medication, Case Rep Dermatol 2014; 6(2):180-4.
Ohn J, Hur K, Park H, Cho S y Mun JH, Dermoscopic patterns of green nail syndrome, J Eur Acad Dermatol Venereol 2021; 35(7):e464-6.
Fujitani S, Moffett KS y Yu V, Pseudomonas aeruginosa. Infectious disease and antimicrobial agent. Disponible en: http://antimicrobe.org/new/ b112.asp. 2017.
Kerr JR, Taylor GW, Rutman A et al., Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine inhibit fungal growth, J Clin Pathol 1999; 52(5):385-7.
Ohn J, Yu DA, Park H, Cho S y Mun JH, Green nail syndrome: analysis of the association with onychomycosis, J Am Acad Dermatol 2020; 83(3):940-2.
Rallis E, Paparizos V, Flemetakis A y Katsambas A, Pseudomonas fingernail infection successfully treated with topical nadifloxacin in hivpositive patients: report of two cases, aids 2010; 24(7):1087-8.
Galletti J, Negri M, Grassi FL, Kioshima-Cotica ES y Svidzinski TIE, Fusarium spp. is able to grow and invade healthy human nails as a single source of nutrients, Eur J Clin Microbiol Infect Dis 2015; 34(9): 1767-72.
Gupta AK, Summerbell RC, Venkataraman M y Quinlan EM, Nondermatophyte mould onychomycosis, J Eur Acad Dermatol Venereol 2021; 35(8):1628-41.
Straten MRV, Balkis MM y Ghannoum MA, The role of nondermatophyte molds in onychomycosis: diagnosis and treatment, Dermatol Ther 2002; 15:89-98.
Moreno G y Arenas R, Other fungi causing onychomycosis, Clin Dermatol 2010; 28:160-3.
Gupta AK, Drummond-Main C, Cooper EA et al., Systematic review of nondermatophyte mold onychomycosis: diagnosis, clinical types, epidemiology, and treatment, J Am Acad Dermatol 2012; 66: 494-502.
Atkinson R, Onychomycosis in elderly chiropody patients, Br J Dermatol 1974; 91:67-72.
Tosti A y Piraccini BM, Proximal subungual onychomycosis due to Aspergillus niger: report of two cases, Br J Dermatol 1998; 139:156-7.
Negroni R, Onychomycosis due to Aspergillus species. En Pasqualotto AC (ed.), Aspergillosis from diagnosis to prevention, Dordrecht, Springer, 2009, pp. 961-71.
Bongomin F, Batac CR, Richardson MD y Denning DW, A review of onychomycosis due to Aspergillus species, Mycopathologia 2018; 183(3):485-93.
Gupta AK, Ryder JE, Baran R, Summerbell RC, Non-dermatophyte onychomycosis, Dermatol Clin 2003; 21(2):257-68.
Baran R, Baran & Dawber’s diseases of the nails and their management, 5ª ed., Hoboken, NJ, Wiley-Blackwell, 2019.
Bereston ES y Waring WS, Aspergillus infection of the nails, Arch Derm Syphilol 1946; 54:552-7.
Falahati M, Ghojoghi A, Abastabar M et al., The first case of total dystrophic onychomycosis caused by Aspergillus clavatus resistant to antifungal drugs, Mycopathologia 2016; 181(3-4):273-7.
Veiga FF, De Castro-Hoshino LV, Sato F et al., Fusarium oxysporum is an onychomycosis etiopathogenic agent, Future Microbiol 2018; 13: 1745-56.
Guilhermetti E, Takahachi G, Shinobu CS y Svidzinski TIE, Fusarium spp. as agents of onychomycosis in immunocompetent hosts, Int J Dermatol 2007; 46(8):822-6.
Tseng SS, Longley BJ, Scher RK et al., Fusarium fingernail infection responsive to fluconazole intermittent therapy, Cutis 2000; 65:352-4.
Baswan S, Kasting GB, Li SK et al., Understanding the formidable nail barrier: a review of the nail microstructure, composition and diseases, Mycoses 2017; 60(5):284-95.
Yang YS, Ahn JJ, Shin MK y Lee MH, Fusarium solani onychomycosis of the thumbnail coinfected with Pseudomonas aeruginosa: report of two cases, Mycoses 2011; 54(2):168-71.
Marchisio VF y Fusconi A, Morphological evidence for keratinolytic activity of Scopulariopsis spp. isolates from nail lesions and the air, Med Mycol 2001; 39:287-94.
Marchisio VF, Fusconi A y Querio FL, Scopulariopsis brevicaulis: a keratinophilic or a keratinolytic fungus, Mycoses 2000; 43:281-92.
Fragner P y Belsan I, Scopulariopsis bainier as causative agent of onychomycoses (mycological and clinical study). Part ii : Clinical study, Acta Univ Carol Med (Praga) 1974; 20(5-6):333-58.
Lizardo C y Lizardo A, Presentación inusual de onicomicosis por Candida albicans, Rev Med Hondur 2012; 80:61-65.
Gai G, Zhiya Y, Dongmei L et al., Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis, Medical Mycology Case Reports 2019; 24:48-50.
Hogan DA y Kolter R, Pseudomonas-Candida interactions: an ecological role for virulence factors, Science 2002; 296(5576):2229-32.
Matsuura H, Senoo A, Saito M y Hamanaka Y, Green nail syndrome, qjm: An International Journal of Medicine 2017; 110(9):609.
Mermel LA, McKay M, Dempsey J y Parenteau S, Pseudomonas surgicalsite infections linked to a healthcare worker with onychomycosis, Infect Control Hosp Epidemiol 2003; 24(10):749-52.
De Almeida HL, Duquia RP, De Castro LA y Rocha NM, Scanning electron microscopy of the green nail, Int J Dermatol 2010; 49(8):962-3.
Gambardella A, Licata G y Argenziano G, Green nail infection by Stenotrophomas maltophila, J Clin Aesthet Dermatol 2019; 12(8):13.
Mulita F, Tchabashvili L, Liolis E et al., Green nail syndrome caused by Citrobacter braakii, Clin Case Rep 2021; 9(5):e04203.
Hengge UR y Bardeli V, Green nails, N Engl J Med 2009; 360:1125.
Piraccini BM, Alessandrini A y Starace M, Onychoscopy: dermoscopy of the nails, Dermatol Clin 2018; 36(4):431-8.
Starace M, Ambrogio F, Bruni F et al., Dermatophytic melanonychia: a case series of an increasing disease, Mycoses 2021; 64:511-9.
Romaszkiewicz A, Slawinska M, Sobjanek M et al., Nail dermoscopy (onychoscopy) is useful in diagnosis and treatment follow-up of the nail mixed infection caused by Pseudomonas aeruginosa and Candida albicans, Adv in Derm and Allergology/Poste, 2018; 35(3): 327.
Leung LK y Harding J, A chemical mixer with dark-green nails, bmj Case Rep 2015; bcr2014209203.
Chelidze K y Lipner SR, Brilliant green staining of the fingernails, Cutis 2020; 105(6):317-8.
Baran R, Occupational nail disorders. En Rustemeyer T, Elsner P, John SM y Maibach HI (eds.), Kanerva’s occupational dermatology, Berlín-Heidelberg, Springer, 2012, pp. 255-64.