2022, Número 04
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Revista Médica Sinergia 2022; 7 (04)
Coriocarcinoma gestacional y no gestacional de ovario
Waterhouse GJ, Díaz GIR
Idioma: Español
Referencias bibliográficas: 24
Paginas:
Archivo PDF: 145.93 Kb.
RESUMEN
El coriocarcinoma de ovario es un tumor de células germinales con una incidencia muy baja, el cual puede ser de tipo gestacional o no gestacional, dependiendo de su etiología. Las pacientes cursan con síntomas muy variados, desde dolor abdominal, sangrado uterino anormal, hasta efectos secundarios causados por la elevación de hCG o producto de las metástasis frecuentemente en pulmón y cerebro. Su diagnóstico es muy difícil y tiende a confundirse con otras patologías ováricas. Generalmente, se necesita ultrasonido, estudios patológicos y genéticos para realizar un diagnóstico acertado. El tratamiento consiste en ciclos de quimioterapia y manejo quirúrgico. La sobrevida depende del estadio al momento del diagnóstico.
REFERENCIAS (EN ESTE ARTÍCULO)
Peng H, Li L, Bi Y. Successful management of nongestational ovarian choriocarcinoma complicated with choriocarcinoma syndrome: A case report and a literature review. Curr Probl Cancer [Internet]. 2020 [cited 2021 Dic 17];44(4):100539. doi: http://dx.doi.org/10.1016/j.currproblcancer.2020.100539
WHO classification of tumours [Internet]. Iarc.fr. [cited 202 Jan 10]. Recovered from: https://publications.iarc.fr/Book-And-Report-Series/Who-Classification-Of-Tumours
Kucera C, Cox-Bauer C, Miller C. Apparent ectopic pregnancy with unexpected finding of a germ cell tumor: A case report. Gynecologic Oncology Reports. 2017 [cited 2021 Dic 08];21(3):31-33. doi: http://dx.doi.org/10.1016/j.gore.2017.05.004
Liu X, Zhang X, Pang Y, Ma Y, Zhang X, Liu P. Clinicopathological factors and prognosis analysis of 39 cases of non-gestational ovarian choriocarcinoma. Arch Gynecol Obstet [Internet]. 2020 [cited 2021 Dic 18];301(4):901–12. doi: http://dx.doi.org/10.1007/s00404-020-05502-9
Zhu C, Liu H, Wei Y, Shen Z, Qian L, Song W et al. Low-risk gestational trophoblastic neoplasia outcome after treatment with VMP regimen from 2005 to 2017. Taiwanese Journal of Obstetrics and Gynecology. 2019 [cited 2021 Dic 08];58(3):332-337. doi: https://doi.org/10.1016/j.tjog.2019.03.008
Zhang X, Yan K, Chen J, Xie X. Using short tandem repeat analysis for choriocarcinoma diagnosis: a case series. Diagn Pathol [Internet]. 2019 [cited 2021 Dic 10];14(1):93. doi: http://dx.doi.org/10.1186/s13000-019-0866-5
Jia N, Chen Y, Tao X, Ou E, Lu X, Feng W. A gestational choriocarcinoma of the ovary diagnosed by DNA polymorphic analysis: a case report and systematic review of the literature. J Ovarian Res [Internet]. 2017 [cited 2021 Dic 08];10(1). doi: http://dx.doi.org/10.1186/s13048-017-0334-3
Maestá I, Ramírez LAC, de Mello JBH, Rudge MVC, Rogatto SR. Genetic characterization of choriocarcinoma and potential clinical implications. Clinics in Oncology - Gynecological Cancers/Oncology [Internet]. 2017.[cited 2021 Nov 11];2. Recovered from: http://www.clinicsinoncology.com/full-text/cio-v2-id1261.php
Kazemi S, Raoufi M, Moghaddam N, Tabatabaeefar M, Ganjooei T. Ovarian ectopic pregnancy misdiagnosed as gestational choriocarcinoma: A case report. Annals of Medicine and Surgery. 2022 [cited 2022 Mar 08];73(4):103236. doi: http://dx.doi.org/10.1016/j.amsu.2021.103236
Duong J, Ghanchi H, Miulli D, Kahlon A. Metastatic nongestational choriocarcinoma to the brain: Case report and proposed treatment recommendations. World Neurosurg [Internet]. 2018 [cited 2021 Nov 08];115:170–5. doi: http://dx.doi.org/10.1016/j.wneu.2018.04.050
Crum CP, Nucci MR, Granter SR, Howitt BE, Parast MM, Boyd T, et al. Diagnostic gynecologic and obstetric pathology [Internet]. 3rd ed. Elsevier; 2017 [cited 2021 Nov 11]. Recovered from: https://books.google.at/books?id=rFk6DwAAQBAJ
Irene M, Njoroge M, Inyangala D, Caroline M, Mariga D, Waweru W, et al. Pure non-gestational ovarian choriocarcinoma. J Pediatr Surg Case Rep [Internet]. 2019 [cited 2021 Nov 14];40:1–5. doi: http://dx.doi.org/10.1016/j.epsc.2018.10.005
Op T, Ghosh A. Ovarian tumors: Pattern of histomorphological types-A 10 years study in a tertiary referral center and review of literature [Internet]. 2016. Com.np. [cited 2022 Mar 08]. Recovered from: http://www.kumj.com.np/issue/54/153-158.pdf
Aranake-Chrisinger J, Huettner P, Hagemann A, Pfeifer J. Use of short tandem repeat analysis in unusual presentations of trophoblastic tumors and their mimics. Human Pathology. 2016 [cited 2021 Nov 18];52(3):92-100. doi: http://dx.doi.org/10.1016/j.humpath.2016.01.005
Magnaeva A, Asaturova A, Tregubova A, Matsneva I, Solopova A. Non-gestational choriocarcinoma of ovary: Clinico-morphological features and diagnostic value of DNA polymorphism study. Human Pathology Reports. 2022 [cited 2022 Mar 08];27(1):300593. doi: https://doi.org/10.1016/j.hpr.2022.300593
Kaur B. Pathology of malignant ovarian germ cell tumours. Diagn Histopathol (Oxf) [Internet]. 2020 [cited 2021 Dic 14]. doi: http://dx.doi.org/10.1016/j.mpdhp.2020.03.006
Savage J, Adams E, Veras E, Murphy KM, Ronnett BM. Choriocarcinoma in women: Analysis of a case series with genotyping. Am J Surg Pathol [Internet]. 2017 [cited 2021 Nov 14];41(12):1593–606. doi: http://dx.doi.org/10.1097/PAS.0000000000000937
Mascilini F, Moro F, Di Grazia FM, Leombroni M, Distefano M, Fanfani F, et al. Clinical and ultrasound features of non-gestational ovarian choriocarcinoma. Ultrasound Obstet Gynecol [Internet]. 2017 [cited 201 Nov 14];52(1):121–3. doi: http://dx.doi.org/10.1002/uog.18943
Quagliozzi L, Lo Presti V, Arciuolo D, Mascilini F. Ultrasound, macroscopic and histological features of malignant ovarian tumors. Non-epithelial ovarian carcinomas: tubal choriocarcinoma and granulosa cell tumor. International Journal of Gynecologic Cancer. 2020 [cited 2021 Nov 20]; 31(7):ijgc-2020-001875. doi: http://dx.doi.org/10.1136/ijgc-2020-001875
Lee A, Im Y, Shim S, Lee S, Kim T, So K. Successful Treatment of Nongestational Choriocarcinoma in a 15-Year-Old Girl: A Case Report. Journal of Pediatric and Adolescent Gynecology. 2021 [cited 2022 Jan 08];34(2):231-233. doi: https://doi.org/10.1016/j.jpag.2020.11.004
Euscher E. Germ Cell Tumors of the Female Genital Tract. Surgical Pathology Clinics. 2019 [cited 2021 Nov 21];12(2):621-649. doi: https://doi.org/10.1016/j.path.2019.01.005
Lee A, Im Y, Shim S, Lee S, Kim T, So K. Successful Treatment of Nongestational Choriocarcinoma in a 15-Year-Old Girl: A Case Report. Journal of Pediatric and Adolescent Gynecology. 2021 [cited 2022 Jan 14];34(2):231-233. doi: https://doi.org/10.1016/j.jpag.2020.11.004
Mello JBH de, Ramos Cirilo PD, Michelin OC, Custódio Domingues MA, Cunha Rudge MV, Rogatto SR, et al. Genomic profile in gestational and non-gestational choriocarcinomas. Placenta [Internet]. 2017 [cited 2021 Nov 19];50:8–15. doi: http://dx.doi.org/10.1016/j.placenta.2016.12.009
Banet N, Gown AM, Shih I-M, Kay Li Q, Roden RBS, Nucci MR, et al. GATA-3 expression in trophoblastic tissues: An immunohistochemical study of 445 cases, including diagnostic utility. Am J Surg Pathol [Internet]. 2015 [cited 2022 Mar 08];39(1):101–8. Recovered from: https://pubmed.ncbi.nlm.nih.gov/25188865/