2020, Número 2
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CorSalud 2020; 12 (2)
Índice neutrófilo-linfocitario: Una herramienta útil en la cardiología intervencionista
Rodríguez BS, Obregón SÁG, Leyva QAY, Gutiérrez RÁR
Idioma: Español
Referencias bibliográficas: 28
Paginas: 209-213
Archivo PDF: 407.34 Kb.
RESUMEN
Las enfermedades cardiovasculares son la principal causa de morbilidad y mortalidad en el mundo, y en Cuba han mostrado un incremento en los últimos años. Su causa isquémica constituye la enfermedad aislada más frecuente de muerte en los cubanos, y el intervencionismo coronario percutáneo (ICP) -como parte de su tratamiento- se encuentra entre las áreas de mayor desarrollo dentro de la Cardiología actualmente. Existe un papel creciente de la inflamación en estas enfermedades, por lo que se impone la búsqueda de nuevos marcadores inflamatorios que tengan relación con este procedimiento. El índice neutrófilo-linfocitario se ha relacionado con la aparición de complicaciones durante el ICP y el seguimiento de estos pacientes, por lo que se propone una actualización al respecto. La evidencia muestra una relación significativa entre el aumento de este índice con la aparición de infarto de miocardio peri-procedimiento, así como con los resultados adversos en el seguimiento; de manera que abre una nueva puerta de investigación en la cardiología intervencionista.
REFERENCIAS (EN ESTE ARTÍCULO)
Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. Heart Disease and Stroke Statistics - 2016 Update: A Report From the American Heart Association. Circulation. 2016;133(4):e38-360.
Ministerio de Salud Pública. Anuario Estadístico de Salud 2017. La Habana: Dirección Nacional de Registros Médicos y Estadísticas de Salud; 2018.
Poludasu S, Cavusoglu E, Khan W, Marmur JD. Neutrophil to lymphocyte ratio as a predictor of long-term mortality in African Americans undergoing percutaneous coronary intervention. Clin Cardiol. 2009;32(12):E6-E10.
Tamhane UU, Aneja S, Montgomery D, Rogers EK, Eagle KA, Gurm HS. Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute coronary syndrome. Am J Cardiol. 2008;102(6):653-7.
Park JJ, Jang HJ, Oh IY, Yoon CH, Suh JW, Cho YS, et al. Prognostic value of neutrophil to lymphocyte ratio in patients presenting with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Am J Cardiol. 2013;111(5):636-42.
Han YC, Yang TH, Kim DI, Jin HY, Chung SR, Seo JS, et al. Neutrophil to Lymphocyte Ratio Predicts Long-Term Clinical Outcomes in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. Korean Circ J. 2013;43(2):93-9.
Herrmann J. Peri-procedural myocardial injury: 2005 update. Eur Heart J. 2005;26(23):2493-519.
Califf RM, Abdelmeguid AE, Kuntz RE, Popma JJ, Davidson CJ, Cohen EA, et al. Myonecrosis after revascularization procedures. J Am Coll Cardiol. 1998;31(2):241-51.
White HD. The prequel: defining prognostically important criteria in the periprocedural PCI troponin saga. Circ Cardiovasc Interv. 2012;5(2):142-5.
Jaffe AS, Apple FS, Lindahl B, Mueller C, Katus HA. Why all the struggle about CK-MB and PCI? Eur Heart J. 2012;33(9):1046-8.
Prasad A, Stone GW, Stuckey TD, Costantini CO, Mehran R, Garcia E, et al. Relation between leucocyte count, myonecrosis, myocardial perfusion, and outcomes following primary angioplasty. Am J Cardiol. 2007;99(8):1067-71.
Fowler AJ, Agha RA. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography - the growing versatility of NLR. Atherosclerosis. 2013;228(1):44-5.
Damman P, Wallentin L, Fox KA, Windhausen F, Hirsch A, Clayton T, et al. Long-term cardiovascular mortality after procedure-related or spontaneous myocardial infarction in patients with non-ST-segment elevation acute coronary syndrome: a collaborative analysis of individual patient data from the FRISC II, ICTUS, and RITA-3 trials (FIR). Circulation. 2012;125(4):568-76.
Moussa ID, Klein LW, Shah B, Mehran R, Mack MJ, Brilakis ES, et al. Consideration of a new definition of clinically relevant myocardial infarction after coronary revascularization: an expert consensus document from the Society for Cardiovascular Angiography and Interventions (SCAI). J Am Coll Cardiol. 2013;62(17):1563-70.
Liou K, Jepson N, Kellar P, Ng B, Isbister J, Giles R, et al. Prognostic significance of peri-procedural myocardial infarction in the era of high sensitivity troponin: A validation of the Joint ACCF/AHA/ESC/WHF Universal Definition of Type 4a Myocardial Infarction with high sensitivity troponin T. Heart Lung Circ. 2015;24(7):673-81.
Feldman DN, Kim L, Rene AG, Minutello RM, Bergman G, Wong SC. Prognostic value of cardiac troponin-I or troponin-T elevation following nonemergent percutaneous coronary intervention: a meta-analysis. Catheter Cardiovasc Interv. 2011;77(7):1020-30.
Arbel Y, Finkelstein A, Halkin A, Birati EY, Revivo M, Zuzut M, et al. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography. Atherosclerosis. 2012;225(2):456-60.
Bressi E, Mangiacapra F, Ricottini E, Cavallari I, Colaiori I, Di Gioia G, et al. Relation of neutrophil to lymphocyte ratio with periprocedural myocardial damage in patients undergoing elective percutaneous coronary intervention. Am J Cardiol. 2016;118(7):980-4.
Stevens LA, Coresh J, Feldman HI, Greene T, Lash JP, Nelson RG, et al. Evaluation of the modification of diet in renal disease study equation in a large diverse population. J Am Soc Nephrol. 2007;18(10):2749-57.
Mohr FW, Morice MC, Kappetein AP, Feldman TE, Stahle E, Colombo A, et al. Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial. Lancet. 2013;381(9867):629-38.
Ellis SG, Guetta V, Miller D, Whitlow PL, Topol EJ. Relation between lesion characteristics and risk with percutaneous intervention in the stent and glycoprotein IIb/IIIa era: An analysis of results from 10,907 lesions and proposal for new classification scheme. Circulation. 1999;100(19):1971-6.
Kaya A, Kurt M, Tanboga IH, Isik T, Günaydin ZY, Kaya Y, et al. Relation of neutrophil to lymphocyte ratio with the presence and severity of stable coronary artery disease. Clin Appl Thromb Hemost. 2014;20(5):473-7.
Jagadish HR, Divyaprakash M, Manjunath R, Girish PG. Association between neutrophil to lymphocyte ratio and severity of coronary artery disease. Int J Adv Med. 2018;5(2):265-70.
Nienhuis MB, Ottervanger JP, Bilo HJ, Dikkeschei BD, Zijlstra F. Prognostic value of troponin after elective percutaneous coronary intervention: A meta-analysis. Catheter Cardiovasc Interv. 2008;71(3):318-24.
Wang X, Zhang G, Jiang X, Zhu H, Lu Z, Xu L. Neutrophil to lymphocyte ratio in relation to risk of all-cause mortality and cardiovascular events among patients undergoing angiography or cardiac revascularization: a meta-analysis of observational studies. Atherosclerosis. 2014;234(1):206-13.
Gibson PH, Croal BL, Cuthbertson BH, Small GR, Ifezulike AI, Gibson G, et al. Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting. Am Heart J. 2007;154(5):995-1002.
Azab B, Zaher M, Weiserbs KF, Torbey E, Lacossiere K, Gaddam S, et al. Usefulness of neutrophil to lymphocyte ratio in predicting short- and long-term mortality after non-ST-elevation myocardial infarction. Am J Cardiol. 2010;106(4):470-6.
Turak O, Ozcan F, Isleyen A, Tok D, Sokmen E, Buyukkaya E, et al. Usefulness of the neutrophil-to-lymphocyte ratio to predict bare-metal stent restenosis. Am J Cardiol. 2012;110(10):1405-1