2021, Número 1
Agrandamiento gingival medicamentoso en pacientes que padecen hipertensión, cardiopatías y epilepsia
Idioma: Español
Referencias bibliográficas: 20
Paginas: 72-80
Archivo PDF: 325.78 Kb.
RESUMEN
Introduction: medicated gingival enlargement is the most widespread undesirable effect of systemic medication on periodontal tissues, the most frequently implicated drugs are phenytoin, cyclosporine and nifedipine, and there is no consensus on exact prevalence figures.Objective: to characterize medicinal gingival enlargement in patients suffering from hypertension, cardiopathy and epilepsy at the Family Physician's Office 21-8 of the "XX Aniversario" Polyclinic.
Methods: a cross-sectional, descriptive, observational study was conducted. Cases were selected by intentional non-probabilistic sampling by criteria, the sample was made up of 46 people. Theoretical and empirical methods were applied that included the application of epidemiological indices. The information was grouped in tables of contingencies and frequencies.
Results: the prevalence of gingival enlargement was 4.3% without distinction of age or sex and it affected those who suffer from epilepsy. Phenytoin and carbamazepine were the drugs that produced it, risk factors were identified: age, sex, time and dose of drug consumption, oral hygiene and periodontal condition.
Conclusions: prevalence of gingival enlargement was low, with severity grade 2 and 3, exclusive of epileptic patients treated with carbamazepine and phenytoin. It affected equally young people of both sexes. Poor oral hygiene and chronic inflammatory periodontal disease were present.
REFERENCIAS (EN ESTE ARTÍCULO)
Morales A, Bravo J, Baeza M, Werlinger F, Gamonala J. Las enfermedades periodontales como enfermedades crónicas no transmisibles: Cambios en los paradigmas. Rev Clin Periodoncia Implantol Rehabil Oral [Internet] 2016 Ago [citado 11/8/2016];9(2): 203-207. Disponible en: https://www.sciencedirect.com/science/article/pii/S0718539116300362. https://doi.org/10.1016/j.piro.2016.07.004
Ministerio de Salud. Orientaciones técnicas para la prevención y tratamiento de las enfermedades gingivales y periodontales [Internet]. Chile: Ministerio de Salud; 2017 [citado 11/8/2018]. Disponible en: https://diprece.minsal.cl/wrdprss_minsal/wp-content/uploads/2018/02/2018.01.23_OT-enfermedades-gingivales-y-periodontales.pdf
Manzur-Villalobos I, Díaz-Rengifo IA, Manzur-Villalobos D, Díaz-Caballero AJ. Agrandamiento gingival farmacoinducido: Serie de casos. Univ Salud [Internet] 2018 [citado 08/09/2018];20(1):89-96. Disponible en: http://www.scielo.org.co/pdf/reus/v20n1/0124-7107-reus-20-01-00089.pdf. http://dx.doi.org/10.22267/rus.182001.113
Ramírez-Rámiz A, Brunet-LLobet L, Lahor-Soler E, Miranda-Riu J. On the cellular and molecular mechanisms of drug-induced gingival overgrowth. Open Dent J [Internet]. 2017 Jul [citado 23/08/2018];11:420-435. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564016/. https://dx.doi.org/10.2174/1874210601711010420
Herrera Giró ML, Acosta González M, Dueñas Herrera A, Armas Rojas NB Noval García R, Castellanos Almeida J. Prevalencia de la Hipertensión Arterial en trabajadores de una institución de salud. Rev Cubana Cardiol Cir Cardiovasc [Internet]. 2017 [citado 07/07/2019];23(2):[aprox. 6 p.]. Disponible en: http://www.revcardiologia.sld.cu/index.php/revcardiologia/article/view/697/pdf_87
James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8). JAMA [Internet]. 2014 Feb [citado 20/12/2019];311(5):507–520. Disponible en: https://jamanetwork.com/article.aspx?doi=10.1001/jama.2013.284427. https://doi.org/10.1001/jama.2013.284427
Pecho Rodríguez CR. Tratamiento de agrandamiento gingival en niños epilépticos tratados con DFH [tesis]. México D.F.: Universidad Nacional Autónoma de México; 2000 [citado 21/12/2019]. Disponible en: https://repositorio.unam.mx/contenidos/tratamiento-de-agrandamiento-gigival-en-ninos-epilepticos-tratados-con-dfh-127504
Román Malo LV. Influencia de los parámetros mitocondriales en el agradamiento gingival inducido por ciclosporina y nifedipina: ensayo sobre modelo animal [tesis]. Sevilla: Universidad de Sevilla; 2016 [citado 03/01/2020]. Disponible en: https://idus.us.es/bitstream/handle/11441/46240/Tesis%20LRom%c3%a1n.pdf?sequence=1&isAllowed=y
Mayorga Rangel C. Agrandamiento gingival asociado a fenitoína: reporte de un caso clínico [tesis]. México D.F.: Universidad Nacional Autónoma de México; 2013 [citado 10/01/2020]. Disponible en: https://repositorio.unam.mx/contenidos/agrandamiento-gingival-asociado-a-fenitoina-reporte-de-un-caso-clinico-375409
Campolo González A, Núñez Castañeda L, Romero Romano P, Rodríguez Schneider A, Fernández Toro MA, Donoso Hofer F. Agrandamiento gingival por ciclosporina: reporte de un caso. Rev Clin Periodoncia Implantol Rehabil Oral [Internet]. 2016 Dic [citado 06/08/2016];9(3):226-230. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0719-01072016000300003. http://dx.doi.org/10.1016/j.piro.2015.05.002