medigraphic.com
Boletín Clínico de la Asociación Médica del Hospital Infantil del Estado de Sonora

2021, Número 1

<< Anterior Siguiente >>

Bol Clin Hosp Infant Edo Son 2021; 38 (1)


Revisión de infección por SARS-CoV-2 en pediatría: presentación de una serie de casos

Cano-Rangel MA, Martínez-Medina MÁ, Frías-Mendívil M, Villegas-Amezaga L, Martínez-Carballo ÉM, Monroy-Zúñiga ÉA

Idioma: Español
Referencias bibliográficas: 29
Paginas: 5-12
Archivo PDF: 174.72 Kb.


RESUMEN

En México, la información sobre las características epidemiológicas y clínicas de los niños infectados con SARSCoV- 2 (Covid-19) son escasos. El objetivo de este trabajo es reportar el espectro de la enfermedad en quince niños infectados por SARS-CoV-2 que requirieron hospitalización en el Hospital Infantil del Estado de Sonora (HIES), durante el periodo de marzo a septiembre de 2020. Las manifestaciones clínicas más frecuentes fueron fiebre (73.3%), dificultad respiratoria (66.7%), artralgias (46.7%) y tos (40%). Nueve (60%) niños fueron confirmados mediante RT-PCR y el resto por IgM-IgG específica. El hallazgo radiológico más común fue la opacidad en vidrio deslustrado. Durante el curso de la hospitalización, ningún paciente requirió cuidados intensivos ni ventilación mecánica invasiva. Se discuten el complejo sintomático y el tratamiento.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Lu X, Xiang Y, Du H, Wing-Kin G. SARS-CoV-2 CoV-2 infection in children – Understanding the immune responses and controlling the pandemic. PAI. [Published online April 24]. 2020. doi: 10.1111/ PAI.13267

  2. Zimmermann P, Curtis N. COVID-19 in Children, Pregnancy and Neonates: A Review of Epidemiologic and Clinical Features. Pediatr Infect Dis J. 2020; 39: 469-477.

  3. Wald E, Schmit K, Gusland D. A Pediatric Infectious Disease Perspective on COVID-19. Clin Infec Disea. 2020; ciaa1095. doi: https://doi.org/10.1093/cid/ ciaa1095

  4. Cano RM. Coronavirus: la tercera oleada del siglo 21. Bol Clin Hosp Infant Edo Son. 2020; 37(1): 1-2.

  5. Wu Z, MacGoogan J. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020; 323(13); 1239-1242.

  6. CDC. Coronavirus Disease 2019 in Children — United States, February 12–April 2, 2020. CDC; 2020. Disponible en: https://www.cdc.gov/coronavirus/ 2019-ncov/downloads/pui-form.pdf

  7. Xiaoxia Lu, Zhang J, et al. SARS-CoV-2 infection in children. N Engl J Med. [Published online March 20]. 2020. doi: 10.1056/NEJMc2005073

  8. Seon-Han M, Hwa-Choy, Hee Chang S, et al. Clinical Characteristic and viral RNA detection in children with coronavirus disease 2019 in the Republic of Korea. JAMA Pediatr. [Published online August 28]. 2020. doi: 10.1001/jamapediatrics.2020.3988

  9. COVID-19 and Multisystem Inflammatory Syndrome in Latin American Children: A Multinational study. Pediatr Infect Dis J. 2021; 40: e1-e6.

  10. Montaño-Luna VE, Pacheco-Rosas DO, et al. Manejo clínico de casos pediátricos de COVID-19. Rev Med Inst Mex Seguro Soc. 2020; 58: 1-13.

  11. Sayampanathan A, Heng CS, Hwee Pin, Pang J, Yee Leong, Lee V. Infectivity of asymptomatic versus symptomatic COCID-19. Lancet. [Published online December 18]. 2020. doi: https://doi.org/10.1016/ S0140-6736(20)32651-9

  12. Montovani A, Netea MG. Trained Innate Immunity, Epigenetics, and Covid-19. N Engl J Med. [Published online September 9]. 2020. doi: 10.1056/NEJMcibr2011679

  13. Giamarellos-Bourboulis EJ, Tsilika M, Moorlag S, Antonakos N, Kotsaki A, Domínguez-Andrés J, et al. Activate: randomized clinical trial of BCG vaccination against infection in the elderly. Cell; 2020. doi: https://doi.org/10.1016/j.cell.2020.08.051

  14. Ellinghaus D, Degenhardt F, et al. The ABO blood group locus and a chromosome 3 gene cluster associate with SARSCoV-2 respiratory failure in an Italian- Spanish genome-wide association analysis. medRxiv. [Published online June 2]. 2020. doi: https:// doi.org/10.1101/2020.05.31.20114991

  15. Tsabouri S, Makis A, Kosmeri C, Siomou E. Risk factors for severity in children with coronavirus-19 disease (COVID-19): A comprehensive literature review. Pediatr Clin N Am. 2021; 68: 321-338.

  16. Cárdenas M, Bustos S, Ann E, Mofenson L, Chakraborty R. Characterizing and Managing Pediatric SARS-CoV-2 Infection. Learning about the Virus in a Global Classroom. Acta Paediatr. [Published online November 1]. 2020. doi: 10.1111/APA.15662

  17. Chen Min Z, Fen Fu J, et al. Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus. World J Clin Pediatr. 2020; 16: 240-246.

  18. Zhong L, Chuan J, Gong B, Shuai P, Zhou Y, Zhang Y, Jiang Z, Zhang D, Liu X, Ma S, et al. Detection of serum IgM and IgG for COVID-19 diagnosis. Sci China Life Sci. [Published online March 25]. 2020. doi: https://doi.org/10.1007/s11427-020-1688-9

  19. Wang D, Hu B, Hu C, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus– Infected Pneumonia in Wuhan, China. JAMA. 2020; 323 (11): 1061-1069.

  20. Zhou G, Chen S, Chen Z. Advances in COVID-19: the virus, the pathogenesis, and evidence-based control y therapeutic strategies. Front Med. 2020; 14(2): 1176-125.

  21. Liang H, Zhang D, Xu J, Dai H, Tang N, Su X, Cao B. SARS-CoV-2 and viral sepsis: observations and hypothesis. Lancet. [Published online April 17]. 2020. doi: https://doi.org/10.1016/S0140- 6736(20)30920-X

  22. Zhang B, Zhou X, Song Y. Immune phenotyping based on neutrophil-to lymphocyte ratio and IgG predicts disease severity and outcome for patients with COVID-19. medRxiv. [Published online March 16]. 2020. doi: https://doi. org/10.1101/2020.03.12.20035048

  23. Mehta P, McAuley D, Brown M, Sánchez E, Tattersal R, Manson J. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. [Published online March 16]. 2020. doi: https://doi. org/10.1016/ S0140-6736(20)30628-0

  24. Kanne J, Little B, Chung JH, Elicker BM, Ketai LH. Essentials for Radiologists on COVID-19: An Update— Radiology Scientific Expert Panel. Radiolo gy. [Published online Feb 27]. 2020. doi: 10.1148/ radiol.2020200527

  25. Zimmermann P, Curtis N. Coronavirus Infections in Children Including COVID-19 An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children. Pediatr Infect Dis J. 2020; 39: 355.

  26. Ding Y, Yan H, Guo W. Clinical characteristics of children with COVID-19: Ameta-analysis. Front. Pediatr. [Published online July 03]. 2020. doi: 10.3389/ fped.2020.00431

  27. Zhou G, Chen S, Chen Z. Advances in COVID-19: the virus, the pathogenesis, and evidence-based control and therapeutic strategies. Front Med. 2020, 14(2): 117-125.

  28. Mishra G, Mulani J. Corticosteroids for COVID-19: the search for an optimum duration of therapy. Lancet Respir Med. [Published online November 26]. 2020. doi: https://doi.org/10.1016/ S2213-2600(20)30530- 0

  29. The RECOVERY Collaborative Group. Dexamethasone in hospitalized patients with Covid-19 — preliminary report. N Engl J Med. doi: 10.1056/NEJMoa2021436




2020     |     www.medigraphic.com