Azuara FH, Nemer CJA, Pulido BJC, Ordoñez RB, Guzmán PCG, Jiménez SA

Idioma: Español
Referencias bibliográficas: 36
Paginas: 9-14
Archivo PDF: 195.58 Kb.

RESUMEN

Objetivo: describir las características epidemiológicas y clínicas al ingreso de pacientes hospitalizados con diagnóstico de COVID-19, en un hospital general en Tabasco, México. Métodos: estudio transversal analítico realizado en el Centro Médico del Instituto de Seguridad Social del Estado de Tabasco (ISSET) “Dr. Julián A. Manzur Ocaña”, en Tabasco, México; del 1 de junio al 31 de julio del 2020, en los módulos de atención de pacientes con diagnóstico sospechosos o confirmados con SARS-COV-2. Resultados: se obtuvo una muestra de 140 casos positivos a SARS-COV-2, 51.42% pertenecía al sexo masculino. Los principales síntomas fueron disnea, tos seca y fiebre. Se observó un mayor incremento de factores inflamatorios y trombóticos en hombres. El tratamiento consistió en antipiréticos, antiagregantes plaquetarios, antimicrobianos y esteroides. El requerimiento de oxígeno suplementario fue similar en mujeres y hombres, sin embargo, la saturación de oxígeno fue mayor en mujeres. Conclusión: la frecuencia de 140 casos positivos a COVID-19, con sintomatología característica de la enfermedad. Con incremento de parámetros inflamatorios y trombóticos. El tratamiento fue sintomático más oxígeno suplementario.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Centers for disease control and prevention. 2019 novel coronavirus, wuhan, china. Information for health care professionals [Internet]. [Citado 2020 Mar 24] Disponible en: https://www.cdc.gov/coronavirus/ 2019- ncov/hcp/index.html

2. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020; 395(10223):507-513.

3. Wang C, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet. 2020;395(10223):470-473.

4. Shereen MA, Khan S, Kazmi A, Bashir N, Siddique R. COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses. J Adv Res. 2020;24:91-98.

5. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395(10223):497-506.

6. WHO. Novel Coronavirus-China. [Internet]. [Citado 2020 Mar 24] Disponible en: http://www. who.int/csr/don/12-january-2020-novel-coronavirus- china/en/

7. WHO. Coronavirus disease (COVID-19) Weekly Epidemiological Update. [Internet]. [Citado 2020 Mar 24] Disponible en: https://www.who.int/emergencies/ diseases/novel-coronavirus-2019/situationreports

8. Adhikari SP, Meng S, Wu YJ, Mao YP, Ye RX, Wang QZ, et al. Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review. Infect Dis Poverty. 2020;9(1):29.

9. Zhang H, Kang Z, Gong H, Xu D, Wang J, Li Z, et al. The digestive system is a potential route of 2019- nCov infection: a bioinformatics analysis based on single-cell transcriptomes. bioRxiv. 2020.

10. Zhang H, Kang Z, Gong H, Xu D, Wang J, Li Z, et al. Digestive system is a potential route of COVID-19: an analysis of single-cell coexpression pattern of key proteins in viral entry process. Gut. 2020;69(6):1010-8.

11. Lauer SA, Grantz KH, Bi Q, Jones FK, Zheng Q, Meredith HR, et al. The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application. Ann Intern Med. 2020;172(9):577-582.

12. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054-1062.

13. Giacomelli A, Pezzati L, Conti F, Bernacchia D, Siano M, Oreni L, Rusconi S, et al. Self-reported Olfactory and Taste Disorders in Patients with Severe Acute Respiratory Coronavirus 2 Infection: A Cross-sectional Study. Clin Infect Dis. 2020;71(15):889-890.

14. Weiss P, Murdoch DR. Clinical course and mortality risk of severe COVID-19. Lancet. 2020 Mar 28;395(10229):1014-1015.

15. Ihle-Hansen H, Berge T, Tveita A, Rønning EJ, Ernø PE, Andersen EL, et al. COVID-19: Symptoms, course of illness and use of clinicals coring systems for the first 42 patients admitted to a Norwegian local hospital. Tidsskr Nor Laegeforen. 2020;140 (7).

16. Christensen DM, Strange JE, Gislason G, Torp-Pedersen C, Gerds T, Fosbøl E, Phelps M. Charlson Comorbidity Index Score and Risk of Severe Outcome and Death in Danish COVID-19 Patients. J Gen Intern Med. 2020;35(9):2801-2803.

17. Pérez Abreu Manuel Ramón, Gómez Tejeda Jairo Jesús, Dieguez Guach Ronny Alejandro. Características clínico-epidemiológicas de la COVID-19. Rev haban cienc méd. 2020;19(2):e3254.

18. Wang W, Xu Y, Gao R, Lu R, Han K, Wu G, Tan W. Detection of SARS-CoV-2 in Different Types of Clinical Specimens. JAMA. 2020;323(18):1843-1844.

19. Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez- Ocampo E, Villamizar-Peña R, Holguin-Rivera Y, Escalera-Antezana JP, et al. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Travel Med Infect Dis. 2020;34:101623.

20. Xie J, Ding C, Li J, Wang Y, Guo H, Lu Z, et al. Characteristics of patients with coronavirus disease (COVID- 19) confirmed using an IgM-IgG antibody test. J Med Virol. 2020;92(10):2004-2010.

21. Zeng F, Dai C, Cai P, Wang J, Xu L, Li J, et al. A comparison study of SARS-CoV-2 IgG antibody between male and female COVID-19 patients: A possible reason underlying different outcome between sex. J Med Virol. 2020; 92(10):2050-2054.

22. Li Z, Yi Y, Luo X, Xiong N, Liu Y, Li S, et al. Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis. J Med Virol. 2020;92(9):1518-1524.

23. Pisanic N, Randad PR, Kruczynski K, Manabe YC, Thomas DL, Pekosz A, et al. COVID-19 Serology at Population Scale: SARS-CoV-2-Specific Antibody Responses in Saliva. J Clin Microbiol. 2020;59(1):e02204-20.

24. SERAM. Guía básica de indicaciones de pruebas de imagen en la infección COVID-19. [Internet]. [Citado 2020 Mar 24] Disponible en: https://seram.es/ images/site/Recomendaciones_imagen_SERAM_ COVID_19.pdf

25. Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, Tao Q, et al. Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020; 296(2):E32-E40.

26. Calvo C, López-Hortelano MG, de Carlos Vicente JC, Vázquez Martínez JL. Recomendaciones sobre el manejo clínico de la infección por el nuevo coronavirus SARS-CoV2. An Pediatr (Barc). 2020;92(4):241. e1-241.e11.

27. Onder G, Rezza G, Brusaferro S. Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy. JAMA. 2020; 323(18):1775- 1776.

28. Porcheddu R, Serra C, Kelvin D, Kelvin N, Rubino S. Similarity in Case Fatality Rates (CFR) of COVID- 19/SARS-COV-2 in Italy and China. J Infect Dev Ctries. 2020;14(2):125-128.

29. Gupta S, Hayek SS, Wang W, Chan L, Mathews KS, Melamed ML, et al. Factors Associated with Death in Critically Ill Patients with Coronavirus Disease 2019 in the US. JAMA Intern Med. 2020;180(11):1-12.

30. Giovanelli L, Quinton R. Androgenicity-not serum testosterone-correlates best with COVID-19 outcome in European males. EBioMedicine. 2021;66:103286.

31. Wan S, Xiang Y, Fang W, Zheng Y, Li B, Hu Y, et al. Clinical features and treatment of COVID-19 patients in northeast Chongqing. J Med Virol. 2020;92 (7):797-806.

32. Shi H, Han X, Jiang N, Cao Y, Alwalid O, Gu J, et al. Radiological findings from 81 patients with COVID- 19 pneumonia in Wuhan, China: a descriptive study. Lancet Infect Dis. 2020;20(4):425-434.

33. Liu F, Li L, Xu M, Wu J, Luo D, Zhu Y, et al. Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19. J Clin Virol. 2020; 127:104370.

34. Fox SE, Akmatbekov A, Harbert JL, Li G, Quincy Brown J, Vander Heide RS. Pulmonary and cardiac pathology in African American patients with COVID- 19: an autopsy series from New Orleans. Lancet Respir Med. 2020;8(7):681-686.

35. Thibodeaux K, Speyrer M, Raza A, Yaakov R, Serena TE. Hyperbaric oxygen therapy in preventing mechanical ventilation in COVID-19 patients: a retrospective case series. J Wound Care. 2020; 29(Sup5a):S4-S8.

36. Despres C, Brunin Y, Berthier F, Pili-Floury S, Besch G. Prone positioning combined with high-flow nasal or conventional oxygen therapy in severe Covid-19 patients. Crit Care. 2020;24(1):256.