2021, Número 6
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Med Int Mex 2021; 37 (6)
Validación de la escala SOAR para desenlaces clínicos en neumonía a gran altitud
Bastidas-Goye AR, Hernández-Bonilla ET, Núñez-Varela JI, Pineda-Vanegas AF, Gómez-Rojas MF, Figueroa-Rodríguez G, Ascencio-Vera MG, Murillo-Silva JA
Idioma: Español
Referencias bibliográficas: 24
Paginas: 920-928
Archivo PDF: 200.91 Kb.
RESUMEN
Objetivo: Evaluar la validez de la escala SOAR para predicción de mortalidad,
requerimiento de ventilación mecánica y admisión a la unidad de cuidado intensivo
en pacientes con neumonía en gran altitud.
Materiales y Métodos: Estudio de cohorte retrospectivo con análisis de validez
para los desenlaces de mortalidad, requerimiento de ventilación mecánica y unidad
de cuidado intensivo (UCI) en pacientes con neumonía, efectuado entre 2015 y 2020
en un hospital a 2630 metros sobre el nivel del mar ubicado en la región de Cundinamarca,
Colombia.
Resultados: Se incluyeron 471 pacientes, el promedio de edad fue de 68.3 ± 19.1,
256 pacientes (54.3%) tenían neumonía severa según la escala SOAR. El área bajo
la curva ROC del puntaje SOAR para mortalidad fue de 0.59 (IC95% 0.511-0.687;
p = 0.029), para ventilación mecánica de 0.50 (IC95% 0.43-0.56; p = 0.946) y para
admisión a UCI de 0.49 (IC95%: 0.43-0.54; p = 0.743) con sensibilidad de mortalidad
del 66.7%, especificidad del 46.9%, valor predictivo positivo del 11.7% y valor
predictivo negativo del 93.9% para un puntaje de corte de 2.
Conclusiones: El puntaje SOAR muestra un rendimiento regular para predicción
de mortalidad en pacientes con neumonía en escenario de gran altitud y no tiene
poder discriminatorio para la predicción de requerimiento de ventilación mecánica
ni admisión a la UCI en estos pacientes.
REFERENCIAS (EN ESTE ARTÍCULO)
Institute for Health Metrics and Evaluation (IHME). Findings from the Global Burden of Disease Study 2017. Seattle WI. 2018.
Ramirez JA, Wiemken TL, Peyrani P, Arnold FW, Kelley R, Mattingly WA, et al. Adults hospitalized with pneumonia in the united states: incidence, epidemiology, and mortality. Clin Infect Dis 2017; 65 (11): 1806-12. doi: 10.1093/ cid/cix647.
Waterer GW, Self WH, Courtney DM, Grijalva CG, Balk RA, Girard TD, et al. In-hospital deaths among adults with community-acquired pneumonia. Chest 2018; 154 (3): 628-35. doi: 10.1016/j.chest.2018.05.021.
Yu H, Rubin J, Dunning S, Li S, Sato R. Clinical and economic burden of community-acquired pneumonia in the Medicare fee-for-service population. J Am Geriatr Soc 2012; 60 (11): 2137-43. doi: 10.1111/j.1532-5415.2012.04208.x.
Martínez-Vernaza S, Mckinley E, Soto MJ, Gualtero- Trujillo S. Neumonía adquirida en la comunidad: una revisión narrativa. Universitas Médica 2018; 59. https:// doi.org/10.11144/Javeriana.umed59-4.neum.
Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K, et al. Diagnosis and treatment of adults with community-acquired pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America. Am J Respir Crit Care Med 2019; 200 (7): e45-e67. doi: 10.1164/ rccm.201908-1581ST.
Corrales-Medina VF, Taljaard M, Fine MJ, Dwivedi G, Perry JJ, Musher DM, et al. Risk stratification for cardiac complications in patients hospitalized for communityacquired pneumonia. Mayo Clinic Proc 2014; 89 (1): 60-8. oi: 10.1016/j.mayocp.2013.09.015.
España PP, Capelastegui A, Gorordo I, Esteban C, Oribe M, Ortega M, et al. Development and validation of a clinical prediction rule for severe community-acquired pneumonia. Am J Respir Crit Care Med 2006; 174 (11): 1249-56. doi: 10.1164/rccm.200602-177OC.
Ahn JH, Choi EY. Expanded A-DROP Score: A new scoring system for the prediction of mortality in hospitalized patients with community-acquired pneumonia. Sci Rep 2018; 8 (1): 14588. https://doi.org/10.1038/s41598-018-32750-2.
Charles PGP, Wolfe R, Whitby M, Fine MJ, Fuller AJ, Stirling R, et al. SMART-COP: A tool for predicting the need for intensive respiratory or vasopressor support in communityacquired pneumonia. Clin Infect Dis 2008; 47 (3): 375-84. doi: 10.1086/589754.
Myint PK, Kamath AV, Vowler SL, Maisey DN, Harrison BDW. Severity assessment criteria recommended by the British Thoracic Society (BTS) for community-acquired pneumonia (CAP) and older patients. Should SOAR (systolic blood pressure, oxygenation, age and respiratory rate) criteria be used in older people? A compilation study of two prospective cohorts. Age Ageing 2006; 35 (3): 286-91. doi: 10.1093/ageing/afj081.
Subramanian DN, Musonda P, Sankaran P, Tariq SM, Kamath AV, Myint PK. Performance of SOAR (systolic blood pressure, oxygenation, age and respiratory rate) scoring criteria in community-acquired pneumonia: a prospective multi-centre study. Age Ageing 2012; 42 (1): 94-7. doi: 10.1093/ageing/afs158.
Perez-Padilla R. Population distribution residing at different altitudes: implications for hypoxemia. Arch Med Res 2002; 33 (2): 162-6. doi: 10.1016/s0188-4409(01)00377-0.
BTS Guidelines for the Management of Community Acquired Pneumonia in Adults. 2001; 56 (suppl 4): iv1-iv64.
Jibaja M, Ortiz-Ruiz G, García F, Garay-Fernández M, de Jesús Montelongo F, Martinez J, et al. Hospital mortality and effect of adjusting PaO2/FiO2 According to altitude above the sea level in acclimatized patients undergoing invasive mechanical ventilation. A multicenter study. Arch Bronconeumol 2020; 56 (4): 218-24. doi: 10.1016/j. arbres.2019.06.024.
Pérez-Padilla JR. Altitude, the ratio of PaO2 to fraction of inspired oxygen, and shunt: impact on the assessment of acute lung injury. Archivos de Bronconeumología (English Edition) 2004; 40 (10): 459-62. https://doi.org/10.1016/ S1579-2129(06)60356-X.
Myint PK, Kamath AV, Vowler SL, Maisey DN, Harrison BD. The CURB (confusion, urea, respiratory rate and blood pressure) criteria in community-acquired pneumonia (CAP) in hospitalised elderly patients aged 65 years and over: a prospective observational cohort study. Age Ageing 2005; 34 (1): 75-7.
Kolditz M, Ewig S, Schutte H, Suttorp N, Welte T, Rohde G. Assessment of oxygenation and comorbidities improves outcome prediction in patients with community-acquired pneumonia with a low CRB-65 score. J Intern Med 2015; 278 (2): 193-202. doi: 10.1111/joim.12349.
Guo Q, Song W-d, Li H-y, Zhou Y-p, Li M, Chen X-k, et al. Scored minor criteria for severe community-acquired pneumonia predicted better. Respiratory Research 2019; 20 (1): 22.
Ehsanpoor B, Vahidi E, Seyedhosseini J, Jahanshir A. Validity of SMART-COP score in prognosis and severity of community acquired pneumonia in the emergency department. Am J Emerg Med 2019; 37 (8): 1450-4. doi: 10.1016/j. ajem.2018.10.044.
Ahnert P, Creutz P, Horn K, Schwarzenberger F, Kiehntopf M, Hossain H, et al. Sequential organ failure assessment score is an excellent operationalization of disease severity of adult patients with hospitalized community acquired pneumonia - results from the prospective observational PROGRESS study. Crit Care 2019; 23 (1): 110. doi: 10.1186/ s13054-019-2316-x.
Aydogdu M, Ozyilmaz E, Aksoy H, Gursel G, Ekim N. Mortality prediction in community-acquired pneumonia requiring mechanical ventilation; values of pneumonia and intensive care unit severity scores. Tuberk Toraks 2010; 58 (1): 25-34.
Buising KL, Thursky KA, Black JF, MacGregor L, Street AC, Kennedy MP, et al. A prospective comparison of severity scores for identifying patients with severe community acquired pneumonia: reconsidering what is meant by severe pneumonia. Thorax 2006; 61 (5): 419-24. doi: 10.1136/ thx.2005.051326.
Shi SJ, Li H, Liu M, Liu YM, Zhou F, Liu B, et al. Mortality prediction to hospitalized patients with influenza pneumonia: PO2/FiO2 combined lymphocyte count is the answer. 2017; 11 (3): 352-60. doi: 10.1111/crj.12346.