2019, Número 627
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Rev Med Cos Cen 2019; 85 (627)
Actualización en guías de manejo endovascular del evento cerebrovascular isquémico agudo
Hernández GA, Odio ZP, Martínez ME, Huete MF, Barboza EMA
Idioma: Español
Referencias bibliográficas: 23
Paginas: 24-29
Archivo PDF: 108.73 Kb.
RESUMEN
Los eventos cerebrovasculares isquémicos son una entidad clínica frecuente y con un gran
impacto en la salud e independencia de los pacientes. Un número importante de estos evolucionan
con un pobre resultado funcional al presentar condiciones que les confiere un pobre pronóstico de
revascularización mediante la trombólisis intravenosa. Ante esto, la trombectomía mecánica ha
venido a ser una opción terapéutica sólida en este tipo de pacientes y aquellos que no resultan
candidatos para la administración de alteplasa intravenosa. En los últimos años se ha generado
nueva evidencia que respalda este abordaje y demuestra su beneficio en nuevos contextos clínicos
para los cuales antes no se tenía ninguna posibilidad de terapia. Por esta razón, las asociaciones
internacionales de stroke se han dado a la tarea de actualizar sus guías y recomendaciones con
relación a este tema con base en la nueva información que se ha publicado recientemente. En este
artículo se pretende establecer los puntos más importantes para definir y abordar un paciente que
se considere puede resultar beneficiado de la realización de trombectomía mecánica
endovascular.
REFERENCIAS (EN ESTE ARTÍCULO)
Smith WS1, Sung G, Starkman S, et al. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke. 2005; 36:1432–1438
Seners P, Turc G, Maïer B, et al. Incidence and Predictors of Early Recanalization After Intravenous Thrombolysis: A Systematic Review and Meta-Analysis. Stroke. 2016; 47: 2409-2412
Malhotra K, Gornbein J & Saver JL. Ischemic Strokes Due to Largevessel Occlusions Contribute Disproportionately to Stroke-Related Dependence and Death: A Review. Front. Neurol. 2017. 8:651. doi: 10.3389/fneur.2017.00651
Clark W, Lutsep H, Barnwell S, et al. The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke. 2009; 40:2761–2768
Powers WJ, Rabinstein AA, Ackerson T, et al “2018 Guidelines for the Early Management of Patients with Acute Ischemic Stroke” Stroke. 2018;49: DOI: 10.1161/STR.0000000000000158
Turc G, Bhogal P, Fischer U, et al. European Stroke Organisation (ESO) - European Society for Minimally Invasive Neurological Therapy (ESMINT) Guidelines on Mechanical Thrombectomy in Acute Ischaemic Stroke. European Stroke Journal 2019, Vol. 4(1) 6–12
Wintermark M1, Albers GW, Broderick JP, et al. Acute Stroke Imaging Research Roadmap II. Stroke. 2013 ;44(9):2628-39. DOI: 10.1161/STROKEAHA.113.002015
Warach SJ, Luby M, Albers GW, et al. Acute Stroke Imaging Research Roadmap III Imaging Selection and Outcomes in Acute Stroke Reperfusion Clinical Trials Consensus Recommendations and Further Research Priorities. Stroke. 2016; 47:1389-1398. DOI: 10.1161/STROKEAHA.115.012364
Seker F, Potreck A, Möhlenbruch M, et al. Comparison of four different collateral scores in acute ischemic stroke by CT angiography. J NeuroIntervent Surg .2015;0:1–4. DOI:10.1136/neurintsurg-2015-012101
Löwhagen Hendén P, Rentzos A, et al. General anesthesia versus conscious sedation for endovascular treatment of acute ischemic stroke: the AnStroke trial (Anesthesia During Stroke). Stroke. 2017; 48:1601–1607. DOI: 10.1161/STROKEAHA.117.016554
Goyal M, Demchuk AM, Menon BK, et al. Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke. N Engl J Med 2015; 372:1019-1030
Saver JL, Goyal M, Bonafe A, et al SWIFT PRIME Investigators. Stentretriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med. 2015; 372:2285–2295. DOI: 10.1056/NEJMoa1415061
Barlinn J, Gerber J, Barlinn K, et al. Acute endovascular treatment delivery to ischemic stroke patients transferred within a telestroke network: a retrospective observational study. Int J Stroke. 2017; 12:502–509. DOI: 10.1177/1747493016681018
Saver JL, Goyal M, van der Lugt A, et al HERMES Collaborators. “Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke: a meta-analysis”. JAMA. 2016; 316:1279–1288. DOI: 10.1001/jama.2016.13647
Aulicky P, Mikulík R, Goldemund D, et al. Safety of performing CT angiography in stroke patients treated with intravenous thrombolysis. J Neurol Neurosurg Psychiatry. 2010; 81:783–787. DOI: 10.1136/jnnp.2009.184002
Krol AL, Dzialowski I, Roy J, et al. Incidence of radiocontrast nephropathy in patients undergoing acute stroke computed tomography angiography. Stroke. 2007; 38:2364–2366. DOI: 10.1161/STROKEAHA.107.482778
Berkhemer OA, Fransen PS, Beumer D, et al MR CLEAN Investigators. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015; 372:11–20. DOI: 10.1056/NEJMoa1411587
Bracard S, Ducrocq X, Mas JL et al. THRACE Investigators. Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomised controlled trial. Lancet Neurol. 2016; 15:1138–1147. DOI: 10.1016/S1474- 4422(16)30177-6
Albers GW, Marks MP, Kemp S, et al. DEFUSE 3 Investigators. Thrombectomy for stroke with perfusion imaging selection at 6–16 hours. N Engl J Med. 2018; 378:708-18
Nogueira RG, Jadhav AP, Haussen DC, et al. TG DAWN Trial Investigators. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct [published online ahead of print November 11, 2017]. N Engl J Med. DOI: 10.1056/NEJMoa1706442
Vilela P & Rowley HA. Brain Ischemia: CT and MRI Techniques in Acute Ischemic Stroke. European Journal of Radiology. 2017: 96: 160-172. DOI: 10.1016/j.ejrad.2017.08.014
Jovin TG, Chamorro A, Cobo E, et al REVASCAT Trial Investigators. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med. 2015; 372:2296–2306. DOI: 10.1056/NEJMoa1503780
Campbell BC, Mitchell PJ, Kleinig TJ, et al EXTEND-IA Investigators. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med. 2015; 372:1009–1018. DOI: 10.1056/NEJMoa1414792