2001, Número 4
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Rev Fac Med UNAM 2001; 44 (4)
La malaria y su sombra: Diagnóstico y tratamiento (fin de la serie)
López AFJ
Idioma: Español
Referencias bibliográficas: 45
Paginas: 177-180
Archivo PDF: 40.16 Kb.
FRAGMENTO
Medición de anticuerpos contra plasmodios
Se han propuesto gran variedad de pruebas, como hemaglutinación indirecta, inmunofluorecencia directa e indirecta, inmunorradiometría y ensayo inmunoabsorbente ligado a enzimas. Los anticuerpos IgG pueden persistir en el suero después de que el paciente ha curado, por lo que no pueden ser usadas estas pruebas para determinar la presencia actual de plasmodios en la sangre. Sin embargo la medición de anticuerpos puede tener gran valor en el estudio seroepidemiológico masivo para analizar la evolución de la malaria retrospectivamente. Los estudios serológicos estandarizados proveen: a) evidencia del establecimiento de tasas de endemicidad, incluyendo prevalencia por especies parasitarias y su distribución por grupos de edad; b) datos sobre cambios en el grado de transmisión en relación a las medidas de control aplicadas; c) delimitación de áreas con transmisión de malaria; d) identificación y seguimiento de focos de transmisión persistente; e) identificación de especie parasitaria y f) tamizaje de donadores de sangre.
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