Córdoba-Vives S, Fonseca-Peñaranda G

Idioma: Español
Referencias bibliográficas: 20
Paginas: 22-29
Archivo PDF: 141.11 Kb.

RESUMEN

El embarazo es considerado como un estado de inmunosupresión parcial que asociado a los cambios fisiológicos y mecánicos hace susceptible a la mujer a distintas infecciones virales, por lo tanto la pandemia por COVID-19 puede tener implicaciones serias en esta población. La mujer embarazada y su feto representan una población vulnerable durante cualquier brote de una enfermedad infecciosa, razón por la cual es importante contar con información actualizada y confiable para la toma de decisiones clínicas. Se presenta a continuación una revisión de literatura reciente incluyendo aspectos inmunológicos, implicaciones clínicas de la enfermedad en pacientes embarazadas, manejo en este grupo específico de pacientes y recomendaciones con respecto al uso de medicamentos, seguimiento y manejo intraparto, para poder abordar oportunamente a la paciente embarazada con COVID-19, con el objetivo de salvaguardar tanto la vida materna como la fetal ante esta enfermedad que hasta hace poco no conocíamos.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Liu H, Wang L-L, Zhao S-J, et al. Why are pregnant women susceptible to COVID-19? An immunological viewpoint. J Reproduct Immunology 2020;139:103122.

2. Wong SF, Chow KM, Leung TN, et al. Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. Am J Obstet Gynecol 2004;191:292-297.

3. Mehta P, McAuley DF, Brown M, et al. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet 2020;395:1033-1034.

4. Favre G, Pomar L, Musso D, Baud D. 2019-nCoV epidemic: what about pregnancies? Lancet 2020;395:e40.

5. Dashraath P, Jing Lin JW, Mei Xian KL, et al. Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy. Am J Obstet Gynecol. 2020;S0002937820303434.

6. Zhu H, Wang L, Fang C, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr 2020;9:51-60.

7. Chen H, Guo J, Wang C, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet 2020;395:809-15.

8. Zeng H, Xu C, Fan J, et al. Antibodies in Infants Born to Mothers With COVID-19 Pneumonia. JAMA 2020 epub ahead of print doi:10.1001/jama.2020.4861

9. Dong L, Tian J, He S, et al. Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn. JAMA 2020 epub ahead of print, doi:10.1001/jama.2020.4621.

10. Liang H, Acharya G. Novel corona virus disease (COVID-19) in pregnancy: What clinical recommendations to follow? Acta Obstet Gynecol Scand 2020;99:439-42.

11. RCOG (Royal College of Obstetricians and Gynecologists). Coronavirus (COVID-19) Infection in Pregnancy Information for healthcare professionals. Consultado el 3 de abril de 2020 en: https://www.rcog.org.uk/globalassets/documents/guideline s/2020-04-17-coronavirus-covid-19-infection-inpregnancy. pdf

12. Ai T, Yang Z, Hou H, et al. Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID- 19) in China: A Report of 1014 Cases. Radiology 2020 epub ahead of print, Doi: 10.1148/radiol.2020200642

13. Liu H, Liu F, Li J, Zhang T, Wang D, Lan W. Clinical and CT imaging features of the COVID-19 pneumonia: Focus on pregnant women and children. Journal of Infection. marzo de 2020;S0163445320301183.

14. Boelig RC, Manuck T, Oliver EA, Di Mascio D, Saccone G, Bellussi F, et al. Labor and Delivery Guidance for COVID-19. American Journal of Obstetrics & Gynecology MFM. marzo de 2020;100110.

15. Kampf G, Todt D, Pfaender S, Steinmann E. Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents. J Hosp Infect 2020;104:246-51.

16. Rasmussen SA, Smulian JC, Lednicky JA ,et al. Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know. American Journal of Obstetrics and Gynecology. 2020, epub ahead of print: doi: 10.1016/j.ajog.2020.02.017

17. Poon LC, Abramowicz JS, Dall’Asta A, et al. ISUOG Safety Committee Position Statement: safe performance of obstetric and gynecological scans and equipment cleaning in the context of COVID-19: ISUOG Safety Committee Position Statement: safe performance of obstetric and gynecological scans and equipment cleaning in the context of COVID-19. Ultrasound Obstet Gynecol 2020 epub ahead of print: doi.wiley.com/10.1002/uog.22027

18. Gautret P, Lagier JC, Parola P, et al. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. Int J Antimicrob Agents 2020 epub ahead of print: doi:10.1016/j.ijantimicag.2020.105949.

19. Saito J, Yakuwa N, Kaneko K, et al. Tocilizumab during pregnancy and lactation: drug levels in maternal serum, cord blood, breast milk and infant serum. Rheumatol 2019;58:1505-1507.

20. Fang L, Karakiulakis G, Roth M. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Lancet Resp Med 2020;8:e21.