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2021, Número 2

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Rev Educ Bioquimica 2021; 40 (2)


Alteraciones metabólicas y funcionales del músculo esquelético y cardíaco en el síndrome metabólico y su papel regulador de la sensibilidad a la insulina

Rodríguez-Correa E, Gómez CB, Clavel-Pérez PI, Contreras-Vargas Y, Carvajal K

Idioma: Español
Referencias bibliográficas: 75
Paginas: 61-75
Archivo PDF: 653.66 Kb.


RESUMEN

En México existe una alta prevalencia de síndrome metabólico entre la población adulta, el mismo porcentaje se asocia a la población sedentaria del país. Una de las alteraciones que acompaña al síndrome metabólico es la resistencia a la insulina, la cual afecta en gran medida al tejido muscular. Ya que el músculo esquelético y cardíaco abarcan el 40.5% del peso corporal y representan un papel importante en el metabolismo energético corporal, son de mayor interés en esta situación. En esta revisión se exploran las alteraciones en el funcionamiento, metabolismo y función endocrina de este tejido derivadas del desarrollo del síndrome metabólico. Se señalan también las aportaciones del ejercicio para el mantenimiento de un estado saludable y el efecto que tiene sobre el tejido muscular esquelético y cardíaco en el control del síndrome metabólico. Por lo tanto, el objetivo de la revisión es presentar información que describa las alteraciones metabólicas y funcionales que sufren los tejidos musculares durante el síndrome metabólico, el papel que tienen como reguladores de la sensibilidad a la insulina, así como las modificaciones consecuentes al ejercicio.


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