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2020, Número 3

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Rev Cubana Cardiol Cir Cardiovasc 2020; 26 (3)


Indicaciones de los Inhibidores del Sistema Renina-Angiotensina-Aldosterona en Pacientes con COVID-19

Rivas EE

Idioma: Español
Referencias bibliográficas: 16
Paginas: 1-3
Archivo PDF: 130.42 Kb.


FRAGMENTO

Estimado editor:

Desde que se produjo el brote de neumonía causada por un nuevo coronavirus en Wuhan, China, en diciembre de 2019, la enfermedad se ha extendido rápidamente por todo el mundo. Después de la identificación del virus (SARS-CoV-2), la Organización Mundial de la Salud (OMS) la denominó como enfermedad por coronavirus 2019 (COVID-19) y pronto el brote fue declarado Emergencia de Salud Pública (pandemia). Desde entonces se ha presentado un desafío sin precedentes a los científicos de todo el mundo intentando identificar drogas efectivas para la prevención y tratamiento de tal enfermedad.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Vaduganathan M, Vardeny O, Michel T, McMurray JJV, Pfeffer MA, Solomon SD. Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19. N Engl J Med 2020;382:1653-9

  2. Li W, Moore MJ, Vasilieva N, Sui J, Wong SK. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 2003; 426: 450-4.

  3. Hoffmann M, Kleine-Weber H, Schroeder S, Krüger N, Herrler T, Erichsen S et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 2020(2); 181: 271-80.e8 Disponible en: https://doi.org/10.1016/j.cell.2020.02.052

  4. Sommerstein R, Grani C. Preventing a COVID-19 pandemic: ACE inhibitors as a potential risk factor for fatal COVID-19. BMJ 2020; 368: m810

  5. Esler M, Esler D. Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic? J Hypertens 2020 March 11 (Epub ahead of print).

  6. Diaz JH. Hypothesis: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19. J Travel Med 2020 March 18 (Epub ahead of print).

  7. Wang Z, Chen Z, Zhang L, Wang X, Hao G, Zhang Z et al. on behalf of the China Hypertension Survey Investigators. Status of hypertension in China: results from the China Hypertension Survey, 2012-2015. Circulation 2018; 137: 2344-56.

  8. Campbell NRC, Zhang X-H. Hypertension in China. Time to Transition From Knowing the Problem to Implementing the Solution. Circulation. 2018;137:2357–9 https://doi.org/10.1161/CIRCULATIONAHA.118.034028

  9. Lu J, Lu Y, Wang X, Li X, Linderman GC, Wu C et al. Prevalence, awareness, treatment, and control of hypertension in China: data from 1・7 million adults in a population-based screening study (China PEACE Million Persons Project). Lancet 2017; 390: 2549-58.

  10. Ferrario CM, Jessup J, Chappell MC, Averill DB, Brosnihan KB, Tallant EA et al. Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation 2005; 111: 2605-10.

  11. Burchill LJ, Velkoska E, Dean RG, Griggs K, Patel SK, Burrell LM. Combination renin-angiotensin system blockade and angiotensin-converting enzyme 2 in experimental myocardial infarction: implications for future therapeutic directions. Clin Sci (Lond) 2012; 123: 649-58. DOI: 10.1042/CS20120162

  12. Rice GI, Thomas DA, Grant PJ, Turner AJ, Hooper NM. Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. Biochem J 2004; 383: 45-51. DOI: 10.1042/bj20040634

  13. Arentz M, Yim E, Klaff L, Lokhandwala S, Riedo FX, Chong M, et al. Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State. JAMA. 2020;323(16):1612-4. doi:10.1001/jama.2020.4326

  14. NIH Panel Issues Guidelines for COVID-19 Treatment, April 22, 2020, https://covid19treatmentguidelines.nih.gov/ visitado: mayo 2, 2020.

  15. American College of Cardiology. HFSA/ACC/AHA statement addresses concerns re: using RAAS antagonists in COVID-19. 2020. Available at: https://www.acc.org/latest-in-cardiology/articles/2020/03/17/08/59/hfsa-acc-aha-statement-addresses-concerns-re-using-raas-antagonists-in-covid-19. visitado: mayo 2, 2020.

  16. Sanders JM, Monogue ML, Jodlowski TZ, Cutrell JB. Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19). A Review. JAMA. 2020;323(18):1824-36. doi:10.1001/jama.2020.6019. visitado: mayo 2, 2020.




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